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[资源] Elsevier-Design and Manufacture of Pharmaceutical Tablets-2015

1.  Introduction  1
1.1  General considerations  1
1.2  Particle sizes  3
1.3  Excipients  4
1.4  Equipment  9
1.5  Mixing of pharmaceutical powders  9
1.6  Design of experiments  11
References  28
2.  Conventional-Release (CR) Tablets  29
2.1  Low-dose tablet by direct compression (DC)  29
2.2  High-dose tablet by direct compression  30
2.3  Low-solubility API, low-dose tablet by wet granulation (WG)  32
2.4  Soluble API, low-dose tablet by wet granulation  34
2.5  Low-solubility API, high-dose tablet by wet granulation  37
2.6  Soluble API, high-dose tablet by wet granulation  39
References  41
3.  Slow-Release (SR) Tablets  43
3.1  Slow-release tablet using a lipophilic release control agent  43
3.2  Slow-release tablet using Eudragit and Methocel as release control agents  45
3.3  Slow-release tablet using a mixture of Methocels as release control agent  47
Reference  50

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2014-11-12 10:03:58, 874.62 K