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《创新药物化学》英文原版下载
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在坛子里看到Jamma兄弟关于迟玉明主译的《创新药物化学》中文版的帖子，如下 http://www.dxy.cn/bbs/post/view? ... amp;tpg=1&age=0 我看过一部分，感觉英文原版的更为地道。这个有朋友也提到过，说在译文中有错误存在。有的朋友也希望能有人共享。 正好手中有英文原版纸版，书名为Practice of Medicinal Chemistry，第二版。于是，哥几个熬通宵，把几百页的英文纸版扫描成PDF文档，有70多MB，上传给大家共享。 该书被誉为药物化学方面的权威书籍，相信大家一定会受益匪浅。 很辛苦的扫描、上传，其中艰辛不为人道。如果只下载不顶贴，兄弟会寒心的！ 原书信息如下： 书名 Practice of Medicinal Chemistry, 2nd ed ISBN-10 0-12-744481-5 作者 C. Wermuth, ed. 出版社 Academic Press, 2003, 624 pp., hard cover 目录 A Brief History Of Drugs; From Plant Extracts To DNA Technology. Medicinal Chemistry: Definition And Objectives, The Three Main Phases Of Drug Activity, Drug And Diseases Classifications. Measurement And Expression Of Drug Effects. Drug Targets: Molecular Mechanisms Of Drug Action. Strategies In The Search For New Lead Compounds Or Original Working Hypotheses. Natural Products As Pharmaceuticals And Sources For Lead Structures. Basics Of Combinatorial Chemistry. The Contribution Of Molecular Biology To Drug Discovery. Electronic Screening: Lead Finding From Database Mining. High-Speed Chemistry Libraries: Assessment Of Drug-Likeness. Web Alert - Using The Internet For Medicinal Chemistry. Molecular Variations In Homologous Series: Vinylogues And Benzologues. Molecular Variations Based On Isosteric Replacements. Ring Transformations. Introduction Of Conformational Restriction And/Or Steric Hindrance. Identical And Non Identical Twin Drugs. Optical Isomerism In Drugs. Application Strategies For The Primary Structure-Activity Relationship Exploration. Specific Substituent Groups. The Role Of Functional Groups In Drug–Receptor Interactions. Compound Properties And Drug Quality. Quantitative Approaches To Structure-Activity Relationships. Structural Aspects Of Drug Action I. Pharmacophore Identification And Receptor Mapping. Three-Dimentional Quantitative Structure-Property Relationships. Protein Crystallography And Drug Discovery. Protein Comparative Modelling And Drug Discovery. The Transition From Agonist To Antagonist Activity: Symmetry And Other Considerations. Design Of Peptidomimetics. The Fate Of Xenobiotics In Living Organisms. Biotransformation Reactions. Chemical Mechanisms Of Toxicity. Basic Knowledge For Designing Safer Drugs. Designing Prodrugs And Bioprecursors. Macromolecular Carriers For Drug Targeting. Preparation Of Water Soluble Compounds Through Salt Formation. Preparation Of Water-Soluble Compounds By Covalent Attachment Of Solubilizing Moieties. Drug Solubilization With Organic Solvents, Surfactants And Lipids. Improvement Of Drug Properties By Cyclodextrins. Chemical And Physicochemical Solutions To Formulation Problems. Discover A Drug Substance, Formulate And Develop It To A Product. Drug Nomenclature. Legal Aspects Of Product Protection. The Consumption And Production Of Pharmaceuticals. 参考 http://www.sigmaaldrich.com/cata ... 819&Brand=SIGMA 最初申请了一些免费的服务器用来和大家共享资源，但是国内的资源很不稳定，申请的服务器也失效了。让我很无奈。 但是大家确实需要这本书，我再申请一个，然后把这本书再发一遍。 这次上传的不是我们的扫描版，而是本人从网上找到的可编辑版本，分为两个部分，下载后解压即可。 下载链接： http://www.box.net/shared/1ic5u99s88 http://www.box.net/shared/10p000nsws |
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