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【答案】应助回帖
感谢参与，应助指数 +1
Recent Progress in the Synthesis of Bifunctional Diethylenetriaminepentaacetic Acid Derivatives Ligand for Magnetic Resonance Imaging Contrast Agent
作者:Wan, FX (Wan, Fuxian)[ 1 ] ; Yu, KC (Yu, Kaichao)[ 2 ]
CHINESE JOURNAL OF ORGANIC CHEMISTRY
卷: 34 期: 4 页: 613-629
DOI: 10.6023/cjoc201310052
出版年: APR 2014
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摘要
Diethylenetriaminepentaacetic acid (DTPA) and its derivatives have been used in chemistry, biology, medicine and many other fields due to their coordination properties, especially, used as magnetic resonance imaging (MRI) contrast agent. Bifunctional-DTPA ligand can be easily and readily linked to various biomolecules. It is of primary importance for the development high relaxation efficiency and/or targeted MRI contrast agents, but the synthesis of bifunctional-DTPA ligand is rather difficult. In this review, various synthetic methods for synthesizing these compounds are summarized.
关键词
作者关键词:magnetic resonance imaging; DTPA; gadolinium-complexes; bifunctional chelator; synthesis
KeyWords Plus:CHAIN ALKYL ESTERS; NEPHROGENIC SYSTEMIC FIBROSIS; L-LYSINE; IN-VIVO; GADOLINIUM COMPLEXES; PHYSICOCHEMICAL CHARACTERIZATION; RELAXATION ENHANCEMENT; LANTHANIDE COMPLEXES; GD(III) COMPLEXES; DTPA DERIVATIVES
作者信息
通讯作者地址: Wan, FX (通讯作者)
Shan Dong Agr Univ, Coll Chem & Mat Sci, Tai An 271018, Shandong, Peoples R China.
地址:
[ 1 ] Shan Dong Agr Univ, Coll Chem & Mat Sci, Tai An 271018, Shandong, Peoples R China
[ 2 ] Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China
电子邮件地址:yukc@163.com
基金资助致谢
基金资助机构 授权号
National Natural Science Foundation of China
20675033
Science and Technology Development of Shandong Province
2013CEX2019
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出版商
SCIENCE PRESS, 16 DONGHUANGCHENGGEN NORTH ST, BEIJING 100717, PEOPLES R CHINA
类别 / 分类
研究方向:Chemistry
Web of Science 类别:Chemistry, Organic
文献信息
文献类型:Review
语种:Chinese
入藏号: WOS:000336107900001
ISSN: 0253-2786
期刊信息
Impact Factor (影响因子): Journal Citation Reports®
其他信息
IDS 号: AH4OM
Web of Science 核心合集中的 "引用的参考文献": 87
Web of Science 核心合集中的 "被引频次": 0
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