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kxli荣誉版主 (正式写手)
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[交流]
求助：哪里可以查到土霉素的基本资料（中文的）
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| 我想知道土霉素的基本资料，不知道在哪里可以查到？ |
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5楼2008-04-14 13:58:37
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3楼2008-04-13 11:10:36
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4楼2008-04-13 14:37:01
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karl2100(金币+1,VIP+0):多谢提供！
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Ph. Eur. 5.5 (Oxytetracycline Dihydrate). A substance produced by the growth of certain strains of Streptomyces rimosus or obtained by any other means. A yellow, crystalline powder. Very slightly soluble in water; dissolves in dilute acid and alkaline solutions. A 1% suspension in water has a pH of 4.5 to 7.5. Store in airtight containers. Protect from light. USP 29 (Oxytetracycline). A pale yellow to tan, odourless crystalline powder, that darkens on exposure to strong sunlight. Soluble 1 in 4150 of water, 1 in 66 of dehydrated alcohol, and 1 in 6250 of ether; sparingly soluble in alcohol; practically insoluble in chloroform; freely soluble in 3N hydrochloric acid and in alkaline solutions. pH of a 1% suspension in water is between 4.5 and 7.0. It loses potency in solutions of pH below 2 and is rapidly destroyed by alkali hydroxide solutions. Store in airtight containers. Protect from light. 土霉素,USP: 浅黄色至棕色，无味结晶粉末，强日光下变黑。一份溶于4150份水，66份无水乙醇，6250份乙醚；难溶于乙醇；不溶于氯仿；极易溶于3N盐酸和碱性溶液。1%水中混悬液pH值4.5-7.0。pH低于2时溶液效价降低，碱性下迅速失效。避光，密闭容器贮存。 Ph. Eur. 5.5 (Oxytetracycline Hydrochloride). A yellow, hygroscopic, crystalline powder. Freely soluble in water; sparingly soluble in alcohol. Solutions in water become turbid on standing owing to the precipitation of oxytetracycline. A 1% solution in water has a pH of 2.3 to 2.9. Store in airtight containers. Protect from light. 盐酸土霉素, EP: 一种黄色易吸潮晶体粉末，极易溶于水，难溶于乙醇。水溶液放置因析出土霉素而变混。1%水溶液pH值2.3-2.9。避光，密闭容器贮存。 USP 29 (Oxytetracycline Hydrochloride). A yellow, odourless, hygroscopic, crystalline powder. It decomposes at temperatures exceeding 180 degrees, and exposure to strong sunlight or temperatures exceeding 90 degrees in moist air causes it to darken. Its potency is diminished in solutions having a pH below 2, and it is rapidly destroyed by alkali hydroxide solutions. Freely soluble in water, but crystals of oxytetracycline separate as a result of partial hydrolysis of the hydrochloride; sparingly soluble in alcohol and in methyl alcohol, and even less soluble in dehydrated alcohol; insoluble in chloroform and in ether. pH of a 1% solution in water is between 2.0 and 3.0. Store in airtight containers. Protect from light. 盐酸土霉素, USP: 一种黄色，无味，吸潮的晶体粉末。超过180℃分解，暴露在强光或超过90℃下潮湿的空气中颜色变黑。当溶液pH值小于2时效价降低，在碱性溶液中迅速失效。极易溶于水，但其盐酸盐部分水解析出土霉素晶体；难溶于乙醇和甲醇，无水乙醇中溶解度更低；不溶于氯仿和乙醚。1%水溶液pH值2.0-3.0。避光，密闭容器贮存。 |
6楼2008-04-14 14:18:12
