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作者: Cui BC1, Yoon I2, Li JZ3, Lee WK4, Shim YK5. 文题: Synthesis and characterization of novel purpurinimides as photosensitizers for photodynamic therapy. 期刊名,年份,卷(期),起止页码: Int J Mol Sci. 2014 May 8;15(5):8091-105. doi: 10.3390/ijms15058091. 收录信息: 请帮忙查sci收录号是否已出！ |
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Synthesis and characterization of novel purpurinimides as photosensitizers for photodynamic therapy. 作者:Cui, Bing Cun; Yoon, Il; Li, Jia Zhu; Lee, Woo Kyoung; Shim, Young Key International journal of molecular sciences 卷:15 期:5 页:8091-105 DOI:10.3390/ijms15058091 出版年:2014 May 08 摘要 A series of novel purpurinimides with long wavelength absorption were designed and synthesized to develop novel and potential photosensitizers. These compounds were investigated through reduction, oxidation, rearrangement reaction and amidation reactions of methyl pheophorbide a. They demonstrated a considerable bathochromic shift of the major absorption band in the red region of the optical spectrum (695-704 nm). Newly synthesized purpurinimides were screened for their antitumor activities, and showed higher photodynamic efficiency against A549 cell lines as compared to purpurin-18 methyl ester. The results revealed the novel purpurinimides could be potential photosensitizers. 作者信息 地址:College of Medicine, Hubei Polytechnic University, Huangshi 435003, China. cuibc928@hotmail.com. 文献信息 文献类型:Journal Article 语种:English PubMed ID:24815070 NLM 唯一 ID:101092791 创建日期: 12 May 2014 电子出版:08 May 2014 国家/地区: Switzerland ISSN:1422-0067 期刊信息 Impact Factor (影响因子): Journal Citation Reports® 其他信息 分主题子库:Index Medicus 状态:In-Data-Review |
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