24小时热门版块排行榜

>论坛更新日志 (3291)
>导师招生 (250)
>文献求助 (224)
>虫友互识 (209)
>休闲灌水 (144)
>考博 (117)
>硕博家园 (116)
>招聘信息布告栏 (84)
>论文投稿 (76)
>基金申请 (75)
>博后之家 (67)
>考研 (49)
>教师之家 (31)
>找工作 (31)
>论文道贺祈福 (29)
>公派出国 (29)

返回列表

【奖励】本帖被评价8次，作者msd2phd增加金币 7 个

当前主题已经存档。

当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖

msd2phd

至尊木虫 (职业作家)

应助: 0 (幼儿园)
贵宾: 0.1
金币: 20826.4
帖子: 4577
在线: 133.3小时
虫号: 88003

[资源] Chirality in Drug Research

Chirality in Drug Research (Methods and Principles in Medicinal Chemistry)

# Publisher: Wiley-VCH
# Number Of Pages: 370
# Publication Date: 2007-01-02

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals.
The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data.

In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions.

With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.

[ Last edited by msd2phd on 2007-11-20 at 20:41 ]

回复此楼