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[求助]有无南开大学分子生物研究所的战友，请教O-(4-乙氧基-丁基)-小檗胺的合成
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一直未找到该合成路线，又无法购买，特求教，谢谢。 一般资料： O-(4-乙氧基-丁基)-小檗胺 英文名：O-(4-ethoxybutyl)berbamine 分子式：C43H52N2O7 分子量：708.9 CAS：106006-09-1 |
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2楼2007-07-18 13:47:20
★
east999(金币+1):无论结果怎样，谢谢了
east999(金币+1):无论结果怎样，谢谢了
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所有的结果如下：好像没有合成的报道 Zhu, Huifang; Liu, Jiewen; Qi, Shuling; Pan, Bing; Zhou, Yuan; Qi, Jing; Yang, Chunzheng; Xiong, Dongsheng; Jiang, Wenguo; Cheng, Yanhong; Zhao, Shixuan; Yang, Ming; Zhang, Yongci; Zou, Linglin; Liu, Juanni. Antitumor activity of a berbamine derivative EBB by inhibiting tumor cell invasion and transfer. Faming Zhuanli Shenqing Gongkai Shuomingshu (2006), 23pp. CODEN: CNXXEV CN 1810247 A 20060802 CAN 145:449178 AN 2006:793422 CAPLUS Pan, Bing; Zhou, Yuan; Qi, Jing; Xiong, Dongsheng; Liu, Jiewen; Qi, Shuling; Cheng, Yanhong; Yang, Chunzheng; Zhu, Huifang. Effect of calmodulin antagonist EBB on invasion of human fibrosarcoma cell HT1080. Zhongguo Yixue Kexueyuan Xuebao (2005), 27(3), 311-314. CODEN: CIHPDR ISSN:1000-503X. CAN 145:448732 AN Fang, Bai-Jun; Yu, Mei-Li; Yang, Shao-Guang; Liao, Lian-Ming; Liu, Jie-Wen; Zhao, Robert C.-H. Effect of O-4-ethoxyl-butyl-berbamine in combination with pegylated liposomal doxorubicin on advanced hepatoma in mice. World Journal of Gastroenterology (2004), 10(7), 950-953. CODEN: WJGAF2 ISSN:1007-9327. CAN 141:360283 AN 2004:375259 CAPLUS Liu, Jiewen; Qi, Shuling; Zhu, Huifang; Zhang, Jinhong; Li, Zhuo; Wang, Tong. The effect of calmodulin antagonist berbamine derivative-EBB on hepatoma in vitro and in vivo. Chinese Medical Journal (Beijing, China, English Edition) (2002), 115(5), 759-762. CODEN: CMJODS ISSN:0366-6999. CAN 138:83012 AN 2002:500645 CAPLUS Zhang, Jinhong; Xu, Naihan; Xu, Chang; Chen, Jiatong; Liu, Huijun; Duan, Jiangyan. Preliminary investigation on mechanism of anticancer by berbamine derivative (EEB) in vitro. Xibao Shengwuxue Zazhi (2001), 23(4), 218-223. CODEN: XISZD3 ISSN:0253-9977. CAN 136:363383 AN 2002:61045 CAPLUS Zheng, Guanghu; Liu, Huazhang. Primary study on effect and mechanisms of hypotension of central calcium in rabbits. Guangdong Yaoxueyuan Xuebao (1999), 15(1), 10-12. CODEN: GYXUF8 CAN 131:139199 AN 1999:280049 CAPLUS Zheng, Guang-Hua; Cheng, Zhong-Lun; Jiang, Jia-Hua. Effects of O-(4-ethoxybutyl)berbamine on isolated frog hearts. Zhongguo Yaoli Xuebao (1998), 19(5), 497-500. CODEN: CYLPDN ISSN:0253-9756. CAN 129:298193 AN 1998:595115 CAPLUS Zhang, Jinhong; Duan, Hongyan; Gen, Zhaohui; Chen, Jiatong; Huang, Jianyin; Li, Xi. Study on the effects of berbamine and its derivatives on proliferation of Bowes cells in vitro. Zhongcaoyao (1997), 28(8), 483-485. CODEN: CTYAD8 ISSN:0253-2670. CAN 128:252608 AN 1998:126131 CAPLUS Wang, Chen-Guang; Ge, Uue-Ping; Chen, Zun-Qi; He, Qi-Yang; Zhang, Hong-Qing. Reversal of resistance of HL60/Har cells to anti-tumor drugs by calmodulin antagonist. Zhongguo Bingli Shengli Zazhi (1995), 11(5), 496-9. CODEN: ZBSZEB ISSN:1000-4718. CAN 124:219626 AN 1996:112957 CAPLUS Liu, Weimin; Zhao, Shixuan; Liu, Jiewen. Inhibitory effects of calmodulin antagonist EBB on cultured fibroblast. Zhongguo Yaolixue Tongbao (1992), 8(5), 374-6. CODEN: ZYTOE8 ISSN:1001-1978. CAN 118:247585 AN 1993:247585 CAPLUS Zhang, Suipo; Xu, Youhan. Inhibition of the activities of calmodulin-dependent calcium, magnesium- ATPase by benzylisoquinolines: structure-activity relationships. Shengwu Huaxue Yu Shengwu Wuli Xuebao (1988), 20(1), 13-20. CODEN: SHWPAU ISSN:0582-9879. CAN 109:124847 AN 1988:524847 CAPLUS Xu, Youhan; Liu, Jian; Zhang, Suipo; Liu, Lisheng. The effect of berbamine derivatives on activated calcium-stimulated magnesium-dependent ATPase in erythrocyte membranes. Biochemical Journal (1987), 248(3), 985-8. CODEN: BIJOAK ISSN:0306-3275. CAN 108:16311 AN 1988:16311 CAPLUS Xu, Youhan; Zhang, Suipo. A derivative of bisbenzylisoquinoline alkaloid is a new and potential calmodulin antagonist. Biochemical and Biophysical Research Communications (1986), 140(1), 461-7. CODEN: BBRCA9 ISSN:0006-291X. CAN 106:27670 AN 1987:27670 CAPLUS Cheng Yan-hong; Qi Jing; Xiong Dong-sheng; Liu Jie-wen; Qi Shu-ling; Pan Bing; Yang Chun-zheng; Zhu Hui-fang Reversal of multidrug resistance in drug-resistant human breast cancer cell line MCF-7/ADR by calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae (2006), 28(2), 164-8. Journal code: 8006230. ISSN:1000-503X. PubMed ID 16733896 AN 2006306455 MEDLINE Pan Bing; Zhou Yuan; Qi Jing; Xiong Dong-sheng; Liu Jie-wen; Qi Shu-ling; Cheng Yan-hong; Yang Chun-zheng; Zhu Hui-fang Effect of calmodulin antagonist EBB on invasion of human fibrosarcoma cell HT1080. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae (2005), 27(3), 311-4. Journal code: 8006230. ISSN:1000-503X. PubMed ID 16038266 AN 2005380752 MEDLINE Fang Bai-Jun; Yu Mei-Li; Yang Shao-Guang; Liao Lian-Ming; Liu Jie-Wen; Zhao Robert C-H Effect of O-4-ethoxyl-butyl-berbamine in combination with pegylated liposomal doxorubicin on advanced hepatoma in mice. World journal of gastroenterology : WJG (2004), 10(7), 950-3. Journal code: 100883448. ISSN:1007-9327. PubMed ID 15052672 AN 2004187605 MEDLINE Liu Jiewen; Qi Shuling; Zhu Huifang; Zhang Jinhong; Li Zhuo; Wang Tong The effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo. Chinese medical journal (2002), 115(5), 759-62. Journal code: 7513795. ISSN:0366-6999. PubMed ID 12133551 AN 2002383504 MEDLINE Zheng G H; Chen Z L; Jiang J H Effects of O-(4-ethoxyl-butyl)-berbamine on isolated frog hearts. Zhongguo yao li xue bao = Acta pharmacologica Sinica (1998), 19(5), 497-500. Journal code: 8100330. ISSN:0253-9756. PubMed ID 10375820 AN 1999304108 MEDLINE Xu Y H; Liu J; Zhang S P; Liu L H The effect of berbamine derivatives on activated Ca2+-stimulated Mg2+-dependent ATPase in erythrocyte membranes. The Biochemical journal (1987), 248(3), 985-8. Journal code: 2984726R. ISSN:0264-6021. PubMed ID 2963623 AN 88133976 MEDLINE Xu Y H; Zhang S P A derivative of bisbenzylisoquinoline alkaloid is a new and potential calmodulin antagonist. Biochemical and biophysical research communications (1986), 140(1), 461-7. Journal code: 0372516. ISSN:0006-291X. PubMed ID 3022722 AN 87048786 MEDLINE |
3楼2007-07-18 20:26:09