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pzt_1984

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yanruo: 金币+1, 翻译EPI+1, 有帮助, Thanks! 2012-07-13 15:39:57
yanruo: 金币+7, ★★★★★最佳答案 2012-08-08 22:21:05
In alkaloids cell toxic mechanism research, alkaloids cells with methylene-dioxy groups present better DNA double helix thermal denaturation stabilizing effect than the cells without methylene-dioxy groups, and inhibit the activity of topoisomerase I via DNA intercalation, this may be one reason why the alkaloids with methylene-dioxy groups have stronger cytotoxicity.
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