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In conclusion, the direction of where smart hydrogels will go in the future should be addressed. Yes, all scientificevidence seems to indicate that basic and translational
research in hydrogels has a bright future. Numerous newdesigns, e.g. involving protein domains containing noncanonicalamino acids , successful attempts to control the morphology of self-assembling peptide fibers ,artificial glycoproteins for controlling cell responses ,hydrogels as the building material for microchemotaxis
devices , enhanced use of DNA recognition motifs,and improved synthetic methods demonstrate the versatility of the hybrid hydrogel approach. An
outstanding example of the potential of stimuli-sensitive hydrogels in the development of bionanotechnology products is the design of optical systems that do not require mechanical components. Jiang¡¯s laboratory developed a tunable liquid lens that permits autonomous focusing. The design was based on a temperature-sensitive hydrogel integrated into a microfluidic system .Obviously, there will be set backs on the way forward, but the scientific and translational potential of hydrogel biomaterials makes me confident in predicting a smart future.
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