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电子云

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[交流] 德国在化学生物学，有机药物化学领域比较有名的教授收集中！ 已有6人参与

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锦上添花易，雪中送炭难！
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yuxia82012

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Professor Dr. Christian Hertweck      
* October 01, 1969

  
Current Status
Professor for Natural Product Chemistry, Friedrich Schiller University Jena
Head of Department Biomolecular Chemistry, Leibniz Institute for Natural Product
Research and Infection Biology - Hans Knöll Institute (HKI)
Beutenbergstraße 11a, 07745 Jena, Phone +49 (0)3641 656700, Fax +49 (0)3641 656705
Email: christian.hertweck@hki-jena.deThis e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Research Interests and Areas of Supervision

microbial secondary metabolism
biosynthesis and pathway engineering of bioactive natural products
symbiotic interactions

Education and Scientific Career

1996 Diploma in Chemistry, University of Bonn
1996 - 1997 Scientific Coworker, University of Bonn
1997 - 1999 Scientific Coworker, Max Planck Institute for Chemical Ecology, Jena
1999 PhD (Dr. rer. nat.), Max Planck Institute for Chemical Ecology, and University of Bonn
1999 - 2000 Postdoctoral fellow (Feodor Lynen), University of Washington, Seattle
2000 - 2005 Leader Junior Research Group, Bioorganic Synthesis, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Jena
2003 - 2005 Commissionary Chair for Natural Product Chemistry, Friedrich Schiller University Jena
2006 Habilitation in Organic Chemistry, Friedrich Schiller University Jena
Since 2006 Full Professor of Natural Product Chemistry, Friedrich Schiller University Jena

Interdisciplinary Affiliation

Since 2006 Faculty member of GRK "International Leibniz Research School for Microbial and Biomolecular Interactions Jena"
Since 2004 Member "DECHEMA Naturstoff-Forum"

Administrative Experience

Since 2005 Referee for DFG
Member of organizational board for Irsee Meeting
Member of Steering Committee in EU project EUKETIDES

Honours and Awards

2005 DECHEMA Award for Natural Products Research
2005 Science Award for Life Sciences and Physics of the Beutenberg Campus
2005 Thuringian Research Award
1999 Feodor Lynen Postdoctoral Fellowship (Alexander von Humboldt Foundation)

Ten most important publications

01. Partida-Martinez LP, Monaienbashi S, Greulich KO, Hertweck C (2007)  -  Maintenance of a bacterial-fungal mutualism through endosymbiont-dependent host sporulation. Curr Biol(in press).
02. Bergmann S, Schümann J, Scherlach K, Lange C, Brakhage AA, Hertweck C (2007)  -  Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans. Nature Chem Biol 3, 213-217.
03. Partida-Martinez LP, Flores de Looß C, Roth M, Buder K, Hertweck C (2007)  -  Rhizonin, the first mycotoxin from zygomycota, is not a fungal metabolite but produced by bacterial endosymbionts. Appl Environ Microbiol 73, 793-797.
04. Scherlach K, Partida-Martinez LP, Dahse HM, Hertweck C (2006)  -  Antimitotic rhizoxin derivatives from a cultured bacterial endosymbiont of the rice pathogenic fungus Rhizopus microsporus. J Am Chem Soc 128, 11529-11536.
05. Müller M, Kusebauch B, Liang G, Beaudry CM, Trauner D, Hertweck C (2006)  -  Photochemical origin of SNF4435C/D and formation of orinocin through ‘Polyene Splicing'. Angew Chem Int Ed 45, 7835-7838.
06. Winkler R, Richter MEA, Knüpfer U, Merten D, Hertweck C (2006)  -  Chemo- and regioselective enzymatic N-Oxygenation in vivo, in vitro, and in flow. Angew Chem Int Ed 45, 8016-8018.
07. Partida-Martinez LP, Hertweck C (2005)  -  Pathogenic fungus harbours endosymbiotic bacteria for toxin production. Nature 437, 884-888.
08. Ziehl M, He J, Dahse HM, Hertweck C (2005)  -  Mutasynthesis of aureonitrile, an aureothin derivative with significantly improved cytostatic effect. Angew Chem Int Ed 44, 1202-1205.
09. Jakobi K, Hertweck C (2004)  -  Cloning and sequencing of the resistomycin biosynthesis gene cluster. exploring polyketide cyclization beyond linear and angucyclic patterns. J Am Chem Soc 126, 2298-2299.
10. He J, Hertweck C (2003)  -  Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster. Chem Biol 10, 1225-1232.

Graduate Teaching and Supervisory Experience

Since 2006 Faculty member of GRK "International Leibniz Research School for Microbial and Biomolecular Interactions Jena"
Since 2004 Member of PhD committees and examiner at doctoral disputations, Friedrich Schiller University Jena
2001 Guest lecturer at the University of Prague

Supervision of Completed Dissertations Since 2001

2004. He, Jing. Molecular analysis of the aureothin biosynthesis gene cluster.
2005. Fritzsche, Kathrin. Kombinatorische Biosynthese von aromatischen Polyketiden.
2005. Herold, Kerstin. Untersuchungen zur Struktur, Wirkungsweise und Biosynthese des Cervimycins als besondere Klasse aromatischer Polyketide aus Streptomyceten.
2006. Loos, Sabine. Expression eukaryotischer PKS in heterologen Wirten.
2006. Traitcheva, Nelly. Untersuchung des Neoaureothin - Biosynthesecluster in Streptomyces orinoci: Ein Modellsystem zur Evolution von bakteriellen Polyketidsynthetasen.
2006. Wangun, Hilaire Kemami. Isolation, structure elucidation and evaluation of anti-inflammatory and anti-infectious activities of fungal metabolites.
2006. Xu, Zhongli. The biosynthesis of benastatin and chartreusin, two structurally intriguing aromatic polyketides.
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在等待中涅槃重生
5楼2011-08-31 19:13:15
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waehrend

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水哥

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何三水，人称水哥（对啦，就是灌水的那个水啦）
2楼2011-08-29 16:00:26
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电子云

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Professor Dr. Richard R. Schmidt
Department of Chemistry
University of Konstanz
Fach M 725
78457 Konstanz, Germany
phone: +49-7531-882538
fax    : +49-7531-883135
e-mail: Richard.Schmidt@uni-konstanz.de


Diploma 1960, University of Stuttgart
Ph.D. 1962, University of Stuttgart
1965/66 Postdoctoral Fellow at The Scripps Research Institute, La Jolla/USA  
Habilitation 1968/69, University of Stuttgart
Professor 1970-75, University of Stuttgart
Since 1975 Professor for Chemistry and Biochemistry, University of Konstanz

Areas of Research
Quinonemethides; Polar 1.4-cycloadditions; Heterocyclic 8p-systems; Nucleosides and derivatives; de novo syntheses of carbohydrates and derivatives via Hetero- Diels-Alder-reactions; Syntheses of butenolides, tetronates, cyclopentenones, lactones, and C-disaccharides via functionally substituted vinyl carbanions and acrylic acid derivatives; Development of glycoside bond formation methodologies; Syntheses of oligosaccharides and glycoconjugates; Syntheses of glycosidase and glycosyltransferase inhibitors; Syntheses of surfactants based on renewable resources; Syntheses of natural products and analogues
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锦上添花易，雪中送炭难！
3楼2011-08-29 18:12:07
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电子云

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Prof. Dr. Manfred T. Reetz
Max-Planck-Institut für Kohlenforschung
Kaiser-Wilhelm-Platz 1
45470 Mülheim an der Ruhr
Germany
Tel. +49-208-306-2000
Fax +49-208-306-2985
E-mail: reetz@mpi-muelheim.mpg.de

Awards and Honors:

1976 Chemical Industries Prize (Dozentenstipendium);
1977 Jacobus van't Hoff Prize (The Netherlands);
1978 Chemistry Prize of the Academy of Sciences Gottingen;
1986 Otto-Bayer-Prize;
1989 Leibniz-Prize of the Deutschen Forschungsgemeinschaft;
since 1997 Member of Deutsche Akademie der Naturforscher Leopoldina;
1997 Fluka-Prize "Reagent of the Year 1997";
2000 Nagoya Gold Medal of Organic Chemistry;
2003 Member of the Kuratorium der Alfried Krupp von Bohlen und Halbach-Stiftung; 2003 Hans Herloff Inhoffen-Medaille.
1980-2003 >120 Plenary Lectures and Name Lectureships.

The primary thrust of their research is the development of chemo- and stereoselective methodologies in organic chemistry, catalytic processes being the main focus. Their efforts are interdisciplinary and can be assigned to four areas of interest:

Development of novel types of chiral ligands for asymmetric transition metal catalysis
Development of supramolecular transition metal catalysts
Preparation and application of water-soluble nanostructured metal oxide colloids
Evolution in the test tube as a means to create enantioselective biocatalysts
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锦上添花易，雪中送炭难！
4楼2011-08-29 18:19:41
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