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【答案】应助回帖
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sltmac(金币+1): 谢谢应助~ 2011-06-27 10:26:58
伊人笑(金币+2, 翻译EPI+1): 多谢，。。。。。。 2011-06-27 21:01:48
sltmac(金币+6): 感谢应助~ 2011-06-30 08:41:29
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A polysaccharide ,from which can sepratede P-1 and P-2 by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography, was extracted from herb-A using ultrasonic-assisted extraction. Then identify the Structural characterizations of P-1 and P-2 ,including molecular weight, monosaccharides composition, sulphate and uronic acid contents, conformational structure, ultraviolet spectrum, and infrared spectrum, and study their anti-proliferation activities against human gastric cancer BGC-823 cells and lung cancer A549 cells in vitro. It can be seen from the research that both P-1 and P-2 can significantly inhibit the proliferation of BGC-823 cells in a certain concentration. The highest inhibitory rates were 78% for P-1 and 95% for P-2 at the concentration of 200 μg/ml. This higher anticancer activity may be attribute to the structural characterization of polysaccharides, and the recognition of biological system for the conformational structure of polysaccharides as well . |
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