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http://www.scbb.szpku.edu.cn/lab ... ?GID=20&UID=105
»Æ œ¥²©Ê¿ Principal Investigator, Pengcheng Professor Tel£º+86-755-2603-5566 Fax£º+86-755-2603-3174 E-mail£ºhuangyong@szpku.edu.cn Web£º
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EDUCATION & EXPERIENCE
2009 ¨C present Professor of Chemistry, Shenzhen Graduate School, Peking
University
2004 ¨C 2009 Senior Research Scientist, Merck Research Laboratories, Merck & Co.,
Rahway, NJ
2002 ¨C 2004 Postdoctoral Scholar, California Institute of Technology, Pasadena,
CA
1997 ¨C 2002 M.Sc. and Ph.D., University of Chicago, Chicago, IL
1993 ¨C 1997 B.Sc., Peking University
FELLOWSHIPS AND AWARDS
2000 Lucent Technologies Travel Grant
2001 Abbott Laboratories Graduate Fellowship
2002 George van Dyke Tiers Travel Award
2002 Elisabeth R. Norton Prize for Excellence
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The group of Dr. Yong Huang has broad interest and extensive experiences in the areas of Medicinal Chemistry, Organic Synthesis, Asymmetric Catalysis and Organometallics. We hope to invent and bring the-state-of-the-art technologies and research strategies to help define a new paradigm in the fields of Chemistry and Chemical Biology. Our research focus includes, but not limited to, the following fields:
1. Total synthesis of biologically active natural products
2. Development of novel chemical transformations for organic synthesis, focusing on asymmetric catalysis
3. Drug discovery: medicinal chemistry from target validation to preclinical
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SELECTIVE PUBLICATIONS
1. Avinash N.Thadani,Yong Huang,and Viresh H.Rawal., "Expedient,High-Yielding Synthesis of Silyl-Substituted Salen Ligands" Org.Lett., 2007, 9, 3873¨C3876.
2. Yong Huang, Abbas M.Walji, Catharine H. Larsen, and David W. C. MacMillan., "Enantioselective Organo-Cascade Catalysis" J.Am.Chem.Soc.; 2005; 127, 15051¨C15053.(100 Current ¡°Hot¡± Papers, National Chemistry Week 2006; For the two consecutive times, rated as the No.1 most cited paper at JACS; Nature research highlight,Vol.437,2005,1068-1069)
3. Yong Huang, Aditya K. Unni, Avinash N. Thadani and Viresh H. Rawal., "Hydrogen Bonding to a Chiral Alcohol Catalyzes Highly Enantioselective Reactions" Nature, 2003, 424, 146. (C&EN Headline, July 14, 2003)
4. Norito Takenaka,Yong Huang,and Viresh H.Rawal.,"The First Catalytic Enantioselective Diels-Alder Reactions of 1,2- Dihydropyridine: Efficient Syntheses of Optically Active 2-Azabicyclo [2.2.2]octanes with Chiral BINAM Derived Cr(III) Salen Complexes" Tetrahedron, 2002, 58, 8299-8305.
5. Yong Huang and Viresh H. Rawal., "Hydrogen Bond Promoted Hetero Diels-Alder Reactions of Ketones" J.Am.Chem.Soc., 2002, 124, 9662-9663.
6. Yong Huang, Tetsuo Iwama, and Viresh H. Rawal., "Design and Development of Highly Effective Lewis Acid Catalysts for Enantioselective Diels-Alder Reactions" J.Am.Chem. Soc.,2002,124,5950-5951.
7. Sergey A. Kozmin, Tetsuo Iwama, Yong Huang, and Viresh H. Rawal., "An Efficient Approach to Aspidosperma Alkaloids via [4+2] Cycloadditions of Aminosiloxydienes: Stereocontrolled Total Synthesis of (¡À)-Tabersonine. Gram-Scale Catalytic Asymmetric Syntheses of (+)- Tabersonine and (+)-16-Methoxytabersonine. Asymmetric Syntheses of (+)-Aspidospermidine and (-)-Quebrachamine" J.Am.Chem.Soc., 2002, 124,4628-4641.
8. Yong Huang, Tetsuo Iwama,and Viresh H. Rawal., "Broadly Effective Enantioselective Diels-Alder Reactions of 1-Amino-substituted-1, 3-butadienes" Org.Lett. 2002, 4, 1163-1166.
9. Yong Huang, Tetsuo Iwama, and Viresh H. Rawal., "Highly Enantioselective Diels-Alder Reactions of 1-Amino-3-siloxy-dienes Catalyzed by Cr(III)-Salen Complexes" J.Am.Chem. Soc.,2000,122,7843-7844.
10. Yong Huang, Viresh. H. Rawal., "Hetero Diels-Alder Reactions of 1-Amino-3-Siloxy-1, 3-butadiene under Strictly Thermal Conditions" Org.Lett.2000,2,3321-3323. |