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2013ÄêÈÙ»ñÈÕ±¾Ñ§ÊõÕñÐË»áJSPSÍâ¹úÈËÌرðÑо¿Ô±Ö°Î»
2010ÄêÈÙ»ñ¹ú¼ÒÁôѧ»ù½ðί½¨Éè¸ßˮƽ´óѧ¹«ÅÉÑо¿ÉúÏîÄ¿½±Ñ§½ð
2010ÄêÈÙ»ñÎ÷±±Å©ÁֿƼ¼´óѧ¶¯ÎïҽѧԺÉÏ°ëÄêѧÊõ±¨¸æ»áÓÅÐã·¢±í¶þµÈ½±
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        2009Äê»ñÎ÷±±Å©ÁֿƼ¼´óѧ 2008-2009 ѧÄê¶ÈУ¼¶ÓÅÐãÑо¿ÉúÈÙÓþ³ÆºÅ
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½üÄêÀ´£¬ÒÔµÚÒ»×÷Õß¼°¹²Í¬×÷ÕßÔÚ¡¶American Journal of Physiology-Endocrinology and Metabolism¡·¡¢¡¶American Journal of Physiology-Cell Physiology¡·¡¢¡¶Chronobiology International¡·¡¢¡¶FEBS Journal¡·¡¢¡¶Biochemical and Biophysical Research Communications¡·¡¢¡¶Journal of reproduction and Development¡·¡¢¡¶Theriogenology¡·¡¢¡¶Frontiers in Endocrinology¡·¡¢¡¶Physiological reports¡·¡¢¡¶ÖйúÅ©Òµ¿Æѧ¡·¡¢¡¶ÖйúÊÞҽѧ±¨¡·¡¢¡¶Å©ÒµÉúÎï¼¼Êõѧ±¨¡·µÈ¿¯ÎïÉÏ·¢±íѧÊõÂÛÎÄ20Óàƪ¡£
2017Äê
Chao Hsu-wen, Doi Masao, Fustin Jean-Michel, Chen Huatao, Murase Kimihiko, Maeda Yuki, Hayashi Hida, Tanaka Rina, Sugawa Maho, Mizuguchi Naoki, Yamaguchi Yoshiaki, Yasunaga Jun-ichirou, Matsuoka Masao, Sakai Mashito, Matsumoto Michihiro, Hamada Shinshichi, Okamura Huitoshi*, A molecular mechanism of hepatic polyploidy unmasked by circadian dysregulation of Mkp1 [J]. Nature Communications, 2017 £¨Under Review£»SCI£» 5-year IF=13.092£» JCR×ÛºÏ1Çø£»ÖпÆÔº×ÛºÏ1Çø£»µÚ4×÷Õߣ©
Xiong Yongjie, Chen Huatao, Lin Pengfei, Wang Aihua, Wang Lei, Jin Yaping*, ATF6 knockdown decreases apoptosis, arrests the S phase of the cell cycle, and increases steroid hormone production in mouse granulosa cells [J]. American Journal of Physiology-Cell Physiology, 312(3): C341-C353, 2017.£¨SCI£»±»Òý´ÎÊý=1´Î£»5-year IF=3.631£» JCRÉúÀíѧ1Çø£»ÖпÆÔºÉúÀíѧ2Çø£»µÚ2×÷Õߣ©
Yang Diqi, Jiang Tingting, Lin Pengfei, Chen Huatao, Wang Lei, Wang Nan, Zhan Fan, Tang Keqiong, Zhou Dong, Wang Aihua, Jin Yaping*, Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line [J]. Reproductive Toxicology, 67: 129-139, 2017. £¨SCI£» 5-year IF=3.202£» JCR¶¾Àíѧ2Çø£»ÖпÆÔº ÉúÖ³ÉúÎïѧ2Çø£»µÚ4×÷Õߣ©
Chen Huatao# *, Gao Lei#, Xiong Yongjie, Yang Dan, Li Cuimei, Wang Aihua, Jin Yaping*, Circadian clock and steroidogenic-related gene expression profiles in mouse Leydig cells following dexamethasone stimulation [J]. Biochemical and Biophysical Research Communications, 483(1): 294-300, 2017. £¨SCI£» 5-year IF=2.354£» JCRÉúÎﻯѧÓë·Ö×ÓÉúÎïѧ3Çø£»ÖпÆÔº ÉúÎïѧ3Çø£»¹²Í¬µÚ1×÷Õߣ¬¹²Í¬Í¨Ñ¶×÷Õߣ©
Yang Diqi, Jiang Tinting, Lin Pengfei, Chen Huatao, Wang Lei, Wang Nan, Zhao Fan, Wang Aihua, Jin Yaping*, Knock-down of apoptosis inducing factor gene protects endoplasmic reticulum stress-mediated goat granulosa cell apoptosis [J]. Theriogenology, 88: 89-97, 2017. £¨SCI£»±»Òý´ÎÊý=3´Î£»5-year IF=2.127£» JCRÊÞҽѧ1Çø£»ÖпÆÔº ÊÞҽѧ2Çø£»µÚ4×÷Õߣ©
Yang Diqi, Wang Lei, Lin Pengfei, Jiang Tingting, Wang Nan, Zhao Fan, Chen Huatao, Tang Keqiong, Zhou Dong, Wang Aihua, Jin Yaping*, An immortalized steroidogenic goat granulosa cells line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis [J]. Journal of reproduction and development, 63(1): 27-36, 2016. (SCI£»±»Òý´ÎÊý=1´Î£»5-year IF=1.585£»JCRÅ©Òµ¡¢ÄÌÖÆÆ·¼°¶¯Îï¿Æѧ1Çø£»ÖпÆԺũҵ¡¢ÄÌÖÆÆ·Ó붯Îï¿Æѧ3Çø£»µÚ7×÷Õß)
2016Äê
Zhu Hongmei#, Hu Linyong#, Liu Jun, Chen Huatao, Cui Chenchen, Song Yujie, Jin Yaping*, Zhang Yong*, Generation of ¦Â-Lactoglobulin-Modified Transgenic goats by Homologous recombination [J]. FEBS Journal, 283(24): 4600-4613, 2016. £¨SCI; 5-year IF=4.129£»JCRÉú»¯Óë·Ö×ÓÉúÎïѧ2Çø£»ÖпÆÔºÉúÎïѧ2Çø£»µÚ4×÷Õߣ©
Zhao lijia, Isayama Keishiro, Chen huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, The nuclear receptor REV-ERB¦Á represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells [J]. Physiological reports, 4(2): e12663, 2016. £¨µÚ3×÷Õߣ©
2015Äê
Chen Huatao, Isayama Keishiro, Kumazawa Makoto, Zhao Lijia, Nobuhiko Yamauchi, Yasufumi Shigeyoshi, Seiichi Hashimoto, Masa-aki Hattori*, Integration of the nuclear receptor REV-ERB¦Á linked to circadian oscillators in the expression of Alas1, Ppargc1a, and Il6 genes in rat granulosa cells [J]. Chronobiology International, 32(6):739-749, 2015. £¨SCI£»±»Òý´ÎÊý=4´Î£»5-year IF=3.056£» JCRÉúÀíѧ2Çø£»ÖпÆÔº ÉúÀíѧ2Çø£¬µÚ1×÷Õߣ©
Tasaki Hirotaka#, Zhao Lijia#, Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, Inhibitory role of REB-ERB¦Á in the expression of bone morphogenetic protein gene family in rat uterus endometrium stromal cells [J]. American Journal of Physiology-Cell Physiology, 308(7): C528-C538, 2015. £¨SCI£»±»Òý´ÎÊý= 5´Î£»5-year IF= 3.631£»JCR ÉúÀíѧ1Çø£»ÖпÆÔº ÉúÀíѧ2Çø£»µÚ4×÷Õߣ©
Isayama Keishiro, Zhao Lijia, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, Removal of REV-ERB¦Á inhibition contributes to prostaglandin G/H synthase 2 expression in rat endometrial stromal cells [J]. American Journal of Physiology-Endocrinology and Metabolism, 308(8): E650-E661, 2015. (SCI£»±»Òý´ÎÊý= 8´Î£»5-year IF= 4.248£»JCR ÉúÀíѧ1Çø£»ÖпÆÔº ÉúÀíѧ2Çø£»µÚ3×÷Õߣ©
2014Äê
Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Hattori Masa-aki*, REV-ERB¦Á Inhibits the PTGS2 Expression in Bovine Uterus Endometrium Stromal and Epithelial Cells Exposed to Ovarian Steroids [J]. Journal of reproduction and development, 60(5): 362-370, 2014. £¨SCI£»±»Òý´ÎÊý=5´Î£»5-year IF=1.585£»JCRÅ©Òµ¡¢ÄÌÖÆÆ·¼°¶¯Îï¿Æѧ1Çø£»ÖпÆԺũҵ¡¢ÄÌÖÆÆ·Ó붯Îï¿Æѧ3Çø£»µÚ2×÷Õߣ©
2013Äê
Chen Huatao, Zhao Lijia, Chu Guiyan, Kito Gakushi, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, FSH induces the development of circadian clockwork in rat granulosa cells via a gap junction protein Cx43-dependent pathway [J]. American Journal of Physiology-Endocrinology and Metabolism, 304(6): E566-E575, 2013. £¨SCI£»±»Òý´ÎÊý= 24´Î£»5-year IF=4.248£»JCR ÉúÀíѧ1Çø£»ÖпÆÔº ÉúÀíѧ2Çø£»µÚ1×÷Õߣ©
Chen Huatao, Zhao Lijia, Kumazawa Makoto, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, Down-regulation of core clock gene Bmal1 attenuates expression of progesterone and prostaglandin biosynthesis-related genes in rat luteinizing granulosa cells [J]. American Journal of Physiology-Cell Physiology, 304(12): C1131-C1140, 2013. £¨SCI£»±»Òý´ÎÊý= 24´Î£»5-year IF= 3.631£»JCR ÉúÀíѧ1Çø£»ÖпÆÔº ÉúÀíѧ2Çø£»µÚ1×÷Õߣ©
Tasaki Hirotaka#, Zhao Lijia#, Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hattori Masa-aki*, Gene profiling of the circadian oscillations in the uterus endometrial stromal cells of pregnant rats by DNA microarray analysis coupled with RNA interference [J]. Frontiers in Endocrinology 4: 82, 2013. £¨SCI£»±»Òý´ÎÊý=10´Î£»IF=3.675£»JCRÄÚ·ÖÃÚÓë´úл2Çø£»µÚ4×÷Õߣ©
2012Äê
Chen Huatao, Chu Guiyan, Zhao Lijia, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, Rev-erb¦Á regulates circadian rhythms and StAR expression in rat granulosa cells as identified by the agonist GSK4112 [J]. Biochemical and Biophysical Research Communications, 420(2): 374-379, 2012. £¨SCI£»±»Òý´ÎÊý= 14´Î£»5-year IF=2.354£»JCRÉúÎﻯѧºÍ·Ö×ÓÉúÎïѧ 3Çø£»ÖпÆÔº ÉúÎïѧ3Çø£»µÚ1×÷Õߣ©
Chu Guiyan, Misawa Izumi, Chen Huatao, Yamauchi Nobuhiko, Shigeyoshi Yasufumi, Hashimoto Seiichi, Hattori Masa-aki*, Contribution of FSH and triiodothyronine to the development of circadian clocks during granulosa cell maturation [J]. American Journal of Physiology-Endocrinology and Metabolism, 302 (6): E645-E653, 2012. £¨SCI£»±»Òý´ÎÊý= 25´Î£»5-year IF= 4.248£»JCR ÉúÀíѧ1Çø£»ÖпÆÔº ÉúÀíѧ2Çø£»µÚ3×÷Õߣ©
2011Äê
³Â»ªÌΣ¬ÀîÙ»£¬ºúÁÖÓ£¬Íõ°®»ª£¬½ùÑÇƽ*£¬Áõ¾ü£¬ÑîÑÞ£¬ÄÌɽÑòBLG»ùÒòÇóýÔØÌåµÄ¹¹½¨ [J]. ÖйúÊÞҽѧ±¨, 31 (6): 858-863, 2011.£¨AÀàÆÚ¿¯£»±»Òý´ÎÊý= 1´Î£»µÚ1×÷Õߣ©
ºúÁÖÓ£¬³Â»ªÌΣ¬ÀîÙ»£¬ÐìÏþ±ò£¬Íõ°®»ª£¬½ùÑÇƽ*£¬É½Ñò¦Â-ÈéÇòµ°°×»ùÒò´ò°ÐÔØÌåµÄ¹¹½¨ [J]. ÖйúÅ©Òµ¿Æѧ, 44 (11): 2364-2370, 2011 £¨AÀàÆÚ¿¯£»±»Òý´ÎÊý= 1´Î£»µÚ2×÷Õߣ©
ÀîÙ»£¬ÐìÏþ±ò£¬³Â»ªÌΣ¬Íõ°®»ª£¬ÕÅÓ¿£¬½ùÑÇƽ*£¬ÂíÑÓÉ­£¬ÇØ´¨Å£ÌìÈ»ÃâÒßÁ¦Ïà¹Ø¾ÞÊÉϸ°ûµ°°×1»ùÒò(Nramp1)N¶ËÐòÁеÄÔ­ºË±í´ï¼°´¿»¯ [J]. Å©ÒµÉúÎï¼¼Êõѧ±¨, 19 (1): 142-148, 2011. £¨AÀàÆÚ¿¯£»±»Òý´ÎÊý=4´Î£»µÚ3×÷Õߣ©
2010Äê
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2008Äê
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Lei Gao, Dan Yang, Cuimei Li, Aihua Wang, Yaping Jin, Huatao Chen. Regulation of Steroidogenic-related genes transcription by circadian clockwork in mouse Leydig cells. µÚ¶þ½ìÑÇÖÞʱ¼äÉúÎïѧÂÛ̳ôßÖйúϸ°ûÉúÎïѧѧ»áÉúÎï½ÚÂÉ·Ö»á2017ÄêѧÊõÄê»á£¬06/2017 £¨ÖйúºôºÍºÆÌØ£¬±Ú±¨£¬ÈÙ»ñ¶þµÈ½±£©
Lei Gao, Cuimei Li, Dan Yang, Aihua Wang, Yaping Jin, Huatao Chen. Usp2-45 acts as a clock controlled gene in the process of deubiquitination. µÚ¶þ½ìÑÇÖÞʱ¼äÉúÎïѧÂÛ̳ôßÖйúϸ°ûÉúÎïѧѧ»áÉúÎï½ÚÂÉ·Ö»á2017ÄêѧÊõÄê»á£¬06/2017 £¨ÖйúºôºÍºÆÌØ£¬ÕªÒª£©
Lei Gao, Huatao Chen, Aihua Wang, Yaping Jin. Regulation of Testosterone Production by Circadian Clock in Mouse Leydig Cells. ÖйúÐóÄÁÊÞҽѧ»áÊÞÒ½²ú¿Æѧ·Ö»á µÚÊ®Èý´ÎѧÊõÑÐÌֻᣬ11/2016£¨ÖйúÄþ²¨£¬±Ú±¨£©
¸ßÀÚ£¬³Â»ªÌΣ¬Íõ°®»ª£¬µÈ. ÉúÎïÖÓ»ùÒòÔÚСÊóغÍè¼äÖÊϸ°ûÖеıí´ï¹æÂÉÑо¿. ÖйúÐóÄÁÊÞҽѧ»á¶¯ÎïÔ°·±Ö³Ñ§·Ö»áµÚÊ®°Ë½ìѧÊõÑÐÌÖ»áôßÖÐÈÕº«µÚËĽ춯ÎﷱֳѧÊõ½»Á÷»á£¬08/2016 £¨ÖйúÄϾ©£¬±Ú±¨£©
Chen Huatao, Isayama Keishiro, Zhao Lijia, et al. REV-ERB¦Á, in conjunction with its ligands, regulates the expression of circadian clockgenes in rat mature granulosa cells. The 106th Society for Reproduction and Development Meeting, 09/2013. (Presentation, Tokyo University of Agriculture and Technology, Japan)
ê? ÈAÌÎ, Úw Á¢¼Ñ, ·þ²¿ ±wÕÃ. Dissection of potential influence of ovarian oscillators on fertility using rat luteinizing granulosa cells,¥ê¥¹¥¯¥µ¥¤¥¨¥ó¥¹Ñо¿¥Õ¥©©`¥é¥à, 03/2013 (Poster, Kyushu University).
Chen Huatao, Zhao Lijia, Yamauchi Nobuhiko, et al. Pivotal role of circadian clock gene Bmal1 in rat luteinizing granulosa cells. International symposium on agriculture, food, environmental and life science in Asia 2012, 10/2012. (Presentation, Chungnam National University, Korea)
Chen Huatao, Zhao Lijia, Yamauchi Nobuhiko, et al. FSH induces the development of circadian clockwork in rat granulosa cells via a gap junction protein Cx43-dependent pathway. The 105th Society for Reproduction and Development Meeting, 2012. (Presentation, University of Tsukuba, Japan)
Chen Huatao, Chu Guiyan, Zhao Lijia, et al. ¥é¥Ã¥È³ÉÊìîwÁ£Ä¤¼š°û¤Ë¤ª¤±¤ë¼š°û•rÓ‹¤ÎÕñ„Ó¤ÈÏÂÁ÷ßz?»×ӤؤÎÓ°í‘. ÈÕ±¾Ðó®bѧ»áµÚ115»Ø´ó»á, 2012. (Presentation, Nagoya University, Japan)
Hattori Masa-aki £¨µ¼Ê¦£©, Chen Huatao, Chu Guiyan, et al.  Rate-Limiting Steps in the Metabolic Pathways of Steroids, Prostaglandins, and Heme Are Controlled Under Cellular Circadian Clocks in Ovarian Granulosa Cells. ICE/ENDO annual meeting, 06/2014. (Chicago, United states).
ÐÜ?É ÕæÇÙ£¬ê? ÈAÌΣ¬É½ÄÚ ÉìÑ壬·þ²¿ ±wÕÃ. ¥×¥í¥é¥¯¥Á¥ó¤ÏÂÑŽzîwÁ£Ä¤¼š°û¤Î•rÓ‹ßz?»×ÓPer2 ¤ÎÕñ„ӵĤʰk¬F¤òµÍϤµ¤»¥×¥í¥¸¥§¥¹¥Æ¥í¥óÉú³É¤òÒÖÖƤ¹¤ë. The 106th Society for Reproduction and Development Meeting, 09/2013. (Poster, Tokyo University of Agriculture and Technology, Japan)
Չɽ »ÛÊ¿ÀÊ£¬ê? ÈAÌΣ¬É½ÄÚ ÉìÑ壬·þ²¿ ±wÕÃ. ¥¦¥·×ÓŒmÄÚĤégÙ|¼š°û¤ª¤è¤ÓÉÏƤ¼š°û¤Ç¤ÏPtgs2£¨Cox2£©°k¬F¤Ï•rÓ‹ßz?»×ÓRev-erb¦Á¤Ë¤è¤Ã¤ÆÒÖÖƵĤËÖÆÓù¤µ¤ì¤Æ¤¤¤ë. The 106th Society for Reproduction and Development Meeting, 09/2013. (Presentation, Tokyo University of Agriculture and Technology, Japan)
Úw Á¢¼Ñ, ê? ÈAÌÎ, ɽÄÚ ÉìÑå, ·þ²¿ ±wÕÃ. Altered levels of steroid hormones affect the expression of circadian rhythm in endometrial stromal cells of pregnant rats,¥ê¥¹¥¯¥µ¥¤¥¨¥ó¥¹Ñо¿¥Õ¥©©`¥é¥à, 03/2013.
Չɽ»ÛÊ¿ÀÊ, ê? ÈAÌÎ, ɽÄÚ ÉìÑå, ·þ²¿ ±wÕÃ,×ÓŒmÄÚĤ¤Î¥×¥í¥¹¥¿¥°¥é¥ó¥¸¥ó·ÖÃÚÖÆÓù¤Ë¤ª¤±¤ë•rÓ‹ßz?»×Ó¤ÎÖØÒªÐÔ,¥ê¥¹¥¯¥µ¥¤¥¨¥ó¥¹Ñо¿¥Õ¥©©`¥é¥à, 03/2013.
Isayama Keishiro, Chen Huatao, Yamauchi Nobuhiko, et al. Circadian rhythms of clock genes and clock-controlled genes in the endometrial stromal cells prepared from the pregnant rat uterus. International symposium on agriculture, food, environmental and life science in Asia, 2012. (Presentation, Chungnam National University, Korea)
Zhao Lijia, Chen Huatao, Yamauchi Nobuhiko, et al. Progesterone alters the phase of circadian rhythms in endometrial stromal cells of pregnant rats. The 105th Society for Reproduction and Development Meeting, 2012. (Poster, University of Tsukuba, Japan)
Hattori Masa-aki, Chu Guiyan, Chen Huatao, et al. FSH¤¬ÂÑŽzδ³ÉÊìîwÁ£Ä¤¼š°û¤Î¼š°û•rÓ‹¤ò°kß_¤µ¤»¤ë. ÈÕ±¾Ðó®bѧ»áµÚ115»Ø´ó»á (2012) (Presentation, Nagoya University, Japan)
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