http://www.ivdshow.cn
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
查看: 1407  |  回复: 107

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

[商家供应] Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测

本商家没有参加优惠活动,一起邀请他来参加吧 我的代金券

代金券0元
限量 x 张
满 x 可使用;有效期 x 天;过期可退

内容

针对特定位点的 m6A RNA甲基化,全球顶级检测方法。具体参考如下:
Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测                                             货号:A-17-10499

Magna MeRIP™ m6A Kit- Transcriptome-wide Profiling of N6-Methyladenosine

背景资料:N6-methyladenosine (m6A) represents an abundant RNA modification that is conserved across many different species, ranging from plants, to yeast, to mammals. Similar to the 5-methylcytosine (5-mc) modification of DNA, m6A is a reversible chemical modification of RNA. m6A RNA modifications are an emerging topic in controlling cell fate transitions in mammalian embryonic stem cells. m6A is one of the most prevalent modifications on both mRNAs and noncoding RNAs in eukaryotes with an estimated 12,000 m6A sites in over 7,000 genes. The mark is deposited by a heterodimer of methyltransferase-like 3 and 14 (Mettl3 and Mettl14) and can be removed by the RNA demethylase enzymes FTO and ALKBH5. Obesity risk gene FTO encodes the first identified m6A demethylase. Mutations in FTO have been associated with increased risk for obesity and type II diabetes. Recently, impairment of the status of m6A regulation has lead to prolonged expression of Nanog in ES cells and the inability to exit self-renewal stages toward differentiation。

产品描述:Methylated (m6A) RNA immunoprecipitation (MeRIP) is a method to monitor the status of m6A and map the location of m6A RNA modifications transcriptome-wide. The Magna MeRIP M6A Kit uses the MeRIP method to enable identification and transcriptome-wide profiling of m6A RNA modifications. In the MeRIP assay, RNA is chemically fragmented into 100 nucleotides or smaller fragments followed by magnetic immunoprecipitation with a monoclonal antibody toward m6A. After immunoprecipitation, isolated RNA fragments can be subjected with qRT-PCR or RNA sequencing (MeRIP-seq). The streamlined protocol is easy to process and can produce results with high SN ratios。

产品特点:

1·Complete collection of MeRIP valiidated reagents to streamline the MeRIP method;

2·High signal to noise ratios using high affinity m6A monoclonal antibody and A/G magnetic beads ;

3.Stem cell validated;

4.The Magna MeRIP M6A Kit provides sufficient reagents for 10 MeRIP reactions using 5 μg of mRNA or 5 MeRIP reactions when 300 μg of total RNA is used;

5.Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals。

保存建议:在接收到艾德寄出的试剂盒后请按照说明书建议,使用不同的保存条件或温度来保存试剂盒内组分。
相关的资料,请下载参考附件。

» 本帖附件资源列表

» 猜你喜欢

» 抢金币啦!回帖就可以得到:

查看全部散金贴

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
本帖仅楼主可见
2楼2017-02-09 09:28:41
已阅   回复此楼   编辑   查看我的主页

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

好产品。
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
3楼2017-02-09 09:29:48
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
4楼2017-02-09 09:48:15
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
5楼2017-02-09 09:50:35
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
6楼2017-02-09 09:50:59
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
7楼2017-02-09 09:52:18
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
·
8楼2017-02-09 09:55:15
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
9楼2017-02-09 09:56:11
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
10楼2017-02-09 09:59:19
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 ADTechnology 的主题更新
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 中药学调剂 初试324 +3 洋甘菊、 2026-04-10 5/250 2026-04-10 23:59 by 洋甘菊、
[考研] 286求调剂 +8 草木不言 2026-04-04 9/450 2026-04-10 23:29 by dc19971224
[考研] 307求调剂 +8 tzq94092 2026-04-10 8/400 2026-04-10 17:33 by 286640313
[考研] 材料专业344求调剂 +16 hualkop 2026-04-10 21/1050 2026-04-10 17:28 by laoshidan
[考研] 一志愿京区985,085401电子信息,本科电子信息 +3 阳光开朗的男孩 2026-04-10 3/150 2026-04-10 16:29 by sophia_93
[考研] 0854求调剂 +5 assdll 2026-04-05 5/250 2026-04-10 15:32 by 高维春
[考研] +6 化工专硕323分 2026-04-04 6/300 2026-04-10 10:04 by may_新宇
[考研] 生物与医药273求调剂 +18 荔题南墙 2026-04-05 19/950 2026-04-10 08:14 by kangsm
[考研] 367求调剂 +10 hffQAQ 2026-04-09 10/500 2026-04-09 18:06 by lijunpoly
[考研] 299求调剂 +6 ZVVZ13 2026-04-08 6/300 2026-04-09 15:48 by wp06
[考研] 270求调剂 +3 031127 2026-04-06 4/200 2026-04-08 21:00 by 逆水乘风
[考研] 263分B区求调剂 +6 李nihao 2026-04-08 6/300 2026-04-08 09:38 by 南开小綦
[考研] 求调剂 +11 wwwwabcde 2026-04-07 11/550 2026-04-07 23:16 by JourneyLucky
[考研] 0854电子信息319求调剂(接受跨专业调剂) +5 星星不眨眼喽 2026-04-05 6/300 2026-04-07 22:16 by hemengdong
[考研] 一志愿西南090202求调剂 +4 在线求有学上 2026-04-07 4/200 2026-04-07 19:47 by biomichael
[考研] 一志愿南科大生物学297分,求调剂推荐 +8 Y-yyusx 2026-04-06 9/450 2026-04-07 19:38 by biomichael
[考研] 材料与化工363求推荐 +11 zh096 2026-04-04 11/550 2026-04-06 19:14 by guanxin1001
[考研] 0817化学工程与技术求调剂,一志愿中海洋319 +14 lv945 2026-04-04 14/700 2026-04-06 10:20 by 蓝云思雨
[考研] 一志愿9材料学硕297已过六级求调剂推荐 +11 adaie 2026-04-04 12/600 2026-04-05 19:04 by 蓝云思雨
[考研] 调剂 +8 熊二想上岸 2026-04-04 8/400 2026-04-05 05:27 by houyaoxu
信息提示
请填处理意见