http://www.ivdshow.cn
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
查看: 1430  |  回复: 107

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

[商家供应] Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测

本商家没有参加优惠活动,一起邀请他来参加吧 我的代金券

代金券0元
限量 x 张
满 x 可使用;有效期 x 天;过期可退

内容

针对特定位点的 m6A RNA甲基化,全球顶级检测方法。具体参考如下:
Magna m6A RNA甲基化免疫沉淀试剂盒-特定位点检测                                             货号:A-17-10499

Magna MeRIP™ m6A Kit- Transcriptome-wide Profiling of N6-Methyladenosine

背景资料:N6-methyladenosine (m6A) represents an abundant RNA modification that is conserved across many different species, ranging from plants, to yeast, to mammals. Similar to the 5-methylcytosine (5-mc) modification of DNA, m6A is a reversible chemical modification of RNA. m6A RNA modifications are an emerging topic in controlling cell fate transitions in mammalian embryonic stem cells. m6A is one of the most prevalent modifications on both mRNAs and noncoding RNAs in eukaryotes with an estimated 12,000 m6A sites in over 7,000 genes. The mark is deposited by a heterodimer of methyltransferase-like 3 and 14 (Mettl3 and Mettl14) and can be removed by the RNA demethylase enzymes FTO and ALKBH5. Obesity risk gene FTO encodes the first identified m6A demethylase. Mutations in FTO have been associated with increased risk for obesity and type II diabetes. Recently, impairment of the status of m6A regulation has lead to prolonged expression of Nanog in ES cells and the inability to exit self-renewal stages toward differentiation。

产品描述:Methylated (m6A) RNA immunoprecipitation (MeRIP) is a method to monitor the status of m6A and map the location of m6A RNA modifications transcriptome-wide. The Magna MeRIP M6A Kit uses the MeRIP method to enable identification and transcriptome-wide profiling of m6A RNA modifications. In the MeRIP assay, RNA is chemically fragmented into 100 nucleotides or smaller fragments followed by magnetic immunoprecipitation with a monoclonal antibody toward m6A. After immunoprecipitation, isolated RNA fragments can be subjected with qRT-PCR or RNA sequencing (MeRIP-seq). The streamlined protocol is easy to process and can produce results with high SN ratios。

产品特点:

1·Complete collection of MeRIP valiidated reagents to streamline the MeRIP method;

2·High signal to noise ratios using high affinity m6A monoclonal antibody and A/G magnetic beads ;

3.Stem cell validated;

4.The Magna MeRIP M6A Kit provides sufficient reagents for 10 MeRIP reactions using 5 μg of mRNA or 5 MeRIP reactions when 300 μg of total RNA is used;

5.Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals。

保存建议:在接收到艾德寄出的试剂盒后请按照说明书建议,使用不同的保存条件或温度来保存试剂盒内组分。
相关的资料,请下载参考附件。

» 本帖附件资源列表

» 猜你喜欢

» 抢金币啦!回帖就可以得到:

查看全部散金贴

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
本帖仅楼主可见
2楼2017-02-09 09:28:41
已阅   回复此楼   编辑   查看我的主页

ADTechnology

捐助贵宾 (著名写手)

表观遗传学专业供应商

好产品。
表观遗传学(m6A RNA甲基化、RNA甲基化、DNA甲基化、DNA羟甲基、DNA甲酰基、DNA羧基),分子生物学,免疫生物学(一抗、二抗),细胞生物学,实验仪器学(核酸提起仪、超微量分光光度计)等等产品与技术服务
北京市昌平区中关村生命科学园东60米艾德园
联系人: Peter Chen / 邮箱: 1951545998@qq.com / QQ: 1513545070 / 电话: 0313-5935521 / 手机: 18911529660
3楼2017-02-09 09:29:48
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
4楼2017-02-09 09:48:15
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
5楼2017-02-09 09:50:35
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
6楼2017-02-09 09:50:59
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
7楼2017-02-09 09:52:18
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
·
8楼2017-02-09 09:55:15
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
9楼2017-02-09 09:56:11
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

ADTechnology(金币+1): 谢谢参与
10楼2017-02-09 09:59:19
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 ADTechnology 的主题更新
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 085410 273求调剂 +5 X1999 2026-04-09 5/250 2026-04-11 17:53 by wj165256
[考研] 270求调剂 +10 杨乐369 2026-04-11 10/500 2026-04-11 16:18 by 明月此时有
[考研] 一志愿085502,267分求调剂 +11 再忙也要吃饭啊 2026-04-08 12/600 2026-04-11 11:08 by zhq0425
[考研] 085600材料与化工329分求调剂 +16 叶zilin 2026-04-10 16/800 2026-04-11 11:04 by may_新宇
[考研] 求调剂 +6 archer.. 2026-04-09 8/400 2026-04-11 10:55 by zhq0425
[考研] 农学0904 312求调剂 +6 Say Never 2026-04-10 6/300 2026-04-11 10:33 by wwj2530616
[考研] 346,工科求调剂 +3 moser233 2026-04-09 3/150 2026-04-11 10:04 by zhq0425
[考研] 342电子信息专硕求调剂 +9 你让我怎么荔枝 2026-04-10 10/500 2026-04-11 08:33 by zhq0425
[考研] 一志愿211,化学学硕,310分,本科重点双非,求调剂 +17 努力奋斗112 2026-04-06 20/1000 2026-04-11 00:31 by wangjihu
[考研] 307求调剂 +8 tzq94092 2026-04-10 8/400 2026-04-10 17:33 by 286640313
[考研] 机械还有还有名额吗?太难了 +6 笑笑袁 2026-04-10 6/300 2026-04-10 11:54 by 高维春
[考研] 材料工程302分求调剂 +18 zyx上岸! 2026-04-04 18/900 2026-04-10 10:07 by 314126402
[考研] 求机械专硕297第二批调剂 +5 拾柒12。 2026-04-08 5/250 2026-04-09 16:43 by 允当适度
[考研] 353求调剂 +8 晴空万里air 2026-04-07 8/400 2026-04-09 00:18 by GouQ
[考研] 计算机408|在校多次国家级竞赛获奖|申请调剂 +4 东山大白鹅 2026-04-05 4/200 2026-04-08 00:18 by chongya
[考研] 277、学硕,求调剂 数一104, +11 瓶子PZ 2026-04-07 12/600 2026-04-07 23:30 by 一只好果子?
[考研] 22408 一志愿双一流人工智能300分 四六级,数据分析国奖 +4 zzfeng123 2026-04-06 6/300 2026-04-07 21:02 by zzfeng123
[考研] 专硕304找调剂,一线城市最好 +3 李lsl李 2026-04-05 3/150 2026-04-06 12:16 by ffffjjjj
[考研] 327求调剂 +4 拾光任染 2026-04-05 4/200 2026-04-05 20:16 by 南航~万老师
[考研] 可跨专业调剂 +3 周的得地 2026-04-04 6/300 2026-04-04 22:21 by barlinike
信息提示
请填处理意见