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小木虫论坛-学术科研互动平台 » 生物医药区 » 生物科学 » 视频：看mRNA如何翻译成蛋白质！经典！不看后悔一辈子！
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bclz

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好，谢谢
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11楼2009-03-16 14:55:02
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chushika
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12楼2009-03-21 20:46:02
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wangtengxu

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想和有趣的人一起做有趣的事。
13楼2009-03-21 23:03:03
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963147963
14楼2009-03-29 21:59:55
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wdyym
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15楼2009-03-29 23:22:42
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tongpei

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英语解说

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错误在所难免，谢谢指正
The job of this mRNA is to carry the gene’s message from the DNA out of the nuclears to a ribosome for a production of a particular protein that this gene codes for. There can be several million ribosomes in a typical eycaryotic cell. This complex catalytic machines use the mRNA copy of the genetic information to a seminal amino acid building blocks into the three dimensional proteins that are essential foe life. Let’s see how it works.
The ribosome’s composed of one large and one small subunit that assemble around the messenger RNA which then passes through the ribosome like a computer tape. The amino acid building blocks that is the small glowing red molecules are carried into the ribosome attached to specific transform RNAs. That’s the green large molecules also referred to as tRNA.
The small subunit of the ribosome positions the mRNA. So they can be read in groups of three letters known as codon. Each codon on the mRNA matches a corresponding to a type of codon on the base of transfor RNA molecule. The large subunit of the ribosome removes each amino acid and joins onto the growing protein chain. As the mRNA is wrenched through the ribosome the mRNA sequence is translated into an amino acid sequence. There are three locations inside the ribosome designated the A Site, the P Site and the E Site.
The addition of each amino acid is three step cycle. First the tRNA enters the ribosome at the A site and is tested for codon and a codon for the entire mRNA. Next provided there is a correct match. The tRNA is shifted to the P Site and the amino acid carries to the end of the amino acid chain. The mRNA is also wrenched on three nucleotides or one codon. Thirdly the spend tRNA is moved to the E Site and then ejected from the ribosome to be recycled. As the protein synthesis proceeds, the finished chain emerges from the ribosome. It folds up to a precise shape determined by the exact order of amino acids. Thus the centre dogma explain has a four letter DNA codes quite literally turned in flesh and blood.
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16楼2009-08-29 14:56:11
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dhmdddd

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谢楼主！！
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上班族，学习ing……
17楼2009-09-08 18:48:00
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ingjye

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thank you very much
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18楼2009-09-09 12:27:58
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