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Annual Reports in Medicinal Chemistry, Volume 43
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Annual Reports in Medicinal Chemistry, Volume 43 By John E. Macor -------------------------------------------------------------------------------- Publisher: Academic Press Number Of Pages: 584 Publication Date: 2008-11-03 ISBN-10 / ASIN: 0123743443 ISBN-13 / EAN: 9780123743442 Binding: Paperback -------------------------------------------------------------------------------- Product Description: Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. * covers findings related to cardiovascular, inflammation, and pulmonary diseases * examines issues in oncology, from mTor inhibitors to drug targets * incorporates up-to-date information on drug design and discovery, including delivery to market Part I: Central Nervous System Diseases 5. Chapter 1 Recent Advances in Corticotropin-Releasing Factor Receptor Antagonists Pages 3-23 Carolyn D. Dzierba, Richard A. Hartz, Joanne J. Bronson Preview Related Articles 6. Chapter 2 Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors Pages 25-42 Brock T. Shireman, Pascal Bonaventure, Nicholas I. Carruthers Preview Related Articles 7. Chapter 3 Recent Advances in Voltage-Gated Sodium Channel Blockers: Therapeutic Potential as Drug Targets in the CNS Pages 43-60 Andreas Termin, Esther Martinborough, Dean Wilson Preview Related Articles 8. Chapter 4 Medication Development for the Treatment of Substance Abuse Pages 61-72 Brian S. Fulton Preview Related Articles Part II: Cardiovascular and Metabolic Diseases 9. Chapter 5 GPR40 (FFAR1) Modulators Pages 75-85 Julio C. Medina, Jonathan B. Houze Preview Related Articles 10. Chapter 6 Rho-Kinase Inhibitors for Cardiovascular Disease Pages 87-102 Robert A. Stavenger Preview Related Articles 11. Chapter 7 LXR Agonists for the Treatment of Atherosclerosis: Recent Highlights Pages 103-117, 565-566 Jonathan Bennett, Andrew Cooke, Heather J. McKinnon, Olaf Nimz Preview Related Articles 12. Chapter 8 Glucagon Receptor Antagonists for Type II Diabetes Pages 119-137 Duane E. DeMong, Michael W. Miller, Jean E. Lachowicz Preview Related Articles Part III: Inflammation/Pulmonary/GI 13. Chapter 9 Advances Toward Dissociated Non-Steroidal Glucocorticoid Receptor Agonists Pages 141-154 John Regan, Hossein Razavi, David Thomson Preview Related Articles 14. Chapter 10 Advances in the Discovery of IκB Kinase Inhibitors Pages 155-170 William J. Pitts, James Kempson Preview Related Articles 15. Chapter 11 Protease Inhibitors for the Potential Treatment of Chronic Obstructive Pulmonary Disease and Asthma Pages 171-185 Weimin Liu, Eugene R. Hickey Preview Related Articles Part IV: Oncology 16. Chapter 12 mTOR Inhibitors in Oncology Pages 189-202 Jeroen Verheijen, Ker Yu, Arie Zask Preview Related Articles 17. Chapter 13 Oncology Drug Targets in the Sphingomyelin-Signaling Pathway Pages 203-226 William Garland, Amy Cavalli, Geneviève Hansen Preview Related Articles Part V: Infectious Diseases 18. Chapter 14 Inhibitors of Respiratory Syncytial Virus Pages 229-245, 567-569 Malcolm Carter, G. Stuart Cockerill Preview Related Articles 19. Chapter 15 Recent Developments in β-Lactamases and Inhibitors Pages 247-267 Tarek S. Mansour, Patricia A. Bradford, Aranapakam M. Venkatesan Preview Related Articles 20. Chapter 16 Recent Development in the Treatment of Clostridium difficile Associated Disease (CDAD) Pages 269-279 Xicheng Sun, Joseph Guiles, Nebojsa Janjic Preview Related Articles 21. Chapter 17 Recent Advances in the Discovery of Hybrid Antibacterial Agents Pages 281-290 Michael R. Barbachyn Preview Related Articles Part VI: Topics in Biology 22. Chapter 18 Recent Renaissance of Prostaglandin Research Pages 293-309 Robert M. Burk Preview Related Articles 23. Chapter 19 Human Exposure and Dose Projections Pages 311-328 Punit H. Marathe, Christine Huang, A. David Rodrigues Preview Related Articles 24. Chapter 20 Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology Approach Pages 329-349 Zoltán Sarnyai, László G. Boros Preview Related Articles Part VII: Topics in Drug Design and Discovery 25. Chapter 21 Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence Absorption Pages 353-371 John M. DeSesso, Amy Lavin Williams Preview Related Articles 26. Chapter 22 The Emerging Utility of Co-Crystals in Drug Discovery and Development Pages 373-404 Nicholas A. Meanwell Preview Related Articles 27. Chapter 23 Pregnane X Receptor: Prediction and Attenuation of Human CYP3A4 Enzyme Induction and Drug–Drug Interactions Pages 405-418 Michael W. Sinz Preview Related Articles 28. Chapter 24 Formulation in Drug Discovery Pages 419-451 Robert G. Strickley Preview Related Articles Part VIII: Trends and Perspectives 29. Chapter 25 To Market, To Market — 2007 Pages 455-497 Shridhar Hegde, Michelle Schmidt Preview Related Articles 30. Compound Name, Code Number and Subject Index, Volume 43 Pages 499-504 Preview Related Articles http://www.namipan.com/d/Annual%20Reports%20in%20Medicinal%20Chemistry%20Vol%2043.pdf/846a09aa31f4cd3ca61545ae35ced3c9703bef24659a6700 |
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