帖子
显示全部
分类 共搜索到 1139 个相关话题(最多显示前5000个) 作者 最后发表
文献求助 不要just accepted版本
JingyaZhangStructure-BasedDesignofNewLSD1/EGFRL858R/T790MDualInhibitorsforTreatingEGFRMutantNSCLCCancersJournalofMedicinalChemistry202568,5,5954–5972...
yyjl0100 2025-12-03 05:55
文献求助 不要just accepted版本
WanqingLiPreclinicalEvaluationofDihydropyrazole-CoredPositronEmissionTomography(PET)LigandsforImagingofReceptor-InteractingSerine/ThreonineProteinKinase1(RIPK1)...
yyjl0100 2025-12-02 05:38
文献求助 不要just accepted版本
TiantianWangTargetingthe“Undruggable”:Small-MoleculeInhibitorsofProliferatingCellNuclearAntigen(PCNA)intheSpotlightinCancerTherapyJournalofMedicinalChemistry20252025,68,3,...
yyjl0100 2025-10-15 05:53
文献求助 不要just accepted版本
SiyuXiuDesign,synthesis,andantitumoractivityofNSDsinhibitorstargetinglungsquamouscellcarcinomaEuropeanJournalofMedicinalChemistry2025Volume289,5May2025,117388...
yyjl0100 2025-10-14 03:57
文献求助 不要just accepted版本
AllenY.HongStereocontrolledFirstGenerationSynthesisofRIPK1InhibitorGDC-8264OrganicProcessResearch&DevelopmentJune20,2025June20,2025...
yyjl0100 2025-10-14 03:02
文献求助 不要just accepted版本
DenizLengerliIsoxazole-pyrimidinederivativesasTACC3inhibitors:AnovelmodalitytotargetedcancertherapyBioorganicChemistry2025Volume156,March2025,108204...
yyjl0100 2025-10-14 01:45
文献求助 不要just accepted 版本,只要正式版本,谢谢
ShellainaJ.V.GordonCatalyticInhibitionofKAT6/KAT7EnhancestheEfficacyandOvercomesPrimaryandAcquiredResistancetoMeninInhibitorsinMLLLeukemiaCancerDiscovAUGUST182025OF1–OF22....
yyjl0100 2025-08-28 01:08
文献求助 不要just accepted 版本,只要正式版本,谢谢
FengXieTargetingFOXM1condensatesreducesbreasttumourgrowthandmetastasisNatureNaturevolume638,pages1112–1121(2025)Naturevolume638,pages1112–1121(2025)...
yyjl0100 2025-08-22 01:01
文献求助 不要just accepted 版本
PaulM.WehnDesignandActivityofSpecificHypoxia-InducibleFactor-2α(HIF-2α)InhibitorsfortheTreatmentofClearCellRenalCellCarcinomaiscoveryofClinicalCandidate(S)-3-((2,2-Difluoro...
yyjl0100 2025-05-12 06:20
文献求助 不要just accepted 版本
DaleiWuBidirectionalmodulationofHIF-2activitythroughchemicalligandsNatureChemicalBiology(2019)volume15,pages367–376(2019)https://www.nature.com/articles/s41589-019-0234-5
yyjl0100 2025-05-09 07:19
文献求助 不要just accepted 版本
JoannaL.ChenTheDiscoveryofBridgedBenzoazepineAmidesasSelectiveAllostericModulatorsofRIPK1ACSMedicinalChemistryLetters202516,5,811–818...
yyjl0100 2025-05-09 02:12
文献求助 不要just accepted版本
JianLiAnon-carboxylativeroutefortheefficientsynthesisofcentralmetabolitemalonyl-CoAanditsderivedproductsNatureCatalysisvolume7,pages361–374(2024)volume7,pages361–374(2024)...
yyjl0100 2025-04-17 09:34
文献求助 不要just accepted 版本,感谢
LitingZhangFromHittoLead:Structure-BasedOptimizationofNovelSelectiveInhibitorsofReceptor-InteractingProteinKinase1(RIPK1)...
yyjl0100 2025-04-02 04:12
文献求助 不要just accepted 版本,感谢
ProfEuniceSWangZiftomenibinrelapsedorrefractoryacutemyeloidleukaemia(KOMET-001):amulticentre,open-label,multi-cohort,phase1trialTheLancetOncologyOctober2024Volume25,Issue10,...
yyjl0100 2025-03-19 02:08
文献求助 不要just accepted版本
KangZhangArtificialintelligenceindrugdevelopmentNatureMedicine20January2025NatureMedicinevolume31,pages45–59(2025)https://www.nature.com/articles/s41591-024-03434-4#:~:text=...
yyjl0100 2025-02-05 07:25
文献求助 不要just accepted版本
BenoitL.SalomonInsightsintothebiologyandtherapeuticimplicationsofTNFandregulatoryTcellsNatureReviewsRheumatology2021volume17,pages487–504(2021...
yyjl0100 2025-01-10 08:09
文献求助 不要just accepted版本
NasirJavaidAnorallyactive,small-moleculeTNFinhibitorthatdisruptsthehomotrimerizationinterfaceimprovesinflammatoryarthritisinmiceScienceSignaling20228Nov2022Vol15,Issue759DOI:10...
yyjl0100 2025-01-10 07:17
文献求助 不要just accepted版本
DanielaSiegmundTNFandTNFreceptorsastherapeutictargetsforrheumaticdiseasesandbeyondnaturereviewsrheumatology19,pages576–591(2023)19,pages576–591(2023)...
yyjl0100 2025-01-10 07:55
文献求助 不要just accepted版本
YushengXiongDiscoveryofaNovelGlucagonReceptorAntagonistN-[(4-{(1S)-1-[3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine(MK-...
yyjl0100 2024-12-31 06:27
文献求助 不要just accepted版本
C.DavidAllisThemolecularhallmarksofepigeneticcontrolnaturereviewsgenetics2016volume17,pages487–500(2016)https://www.nature.com/articles/nrg.2016.59Nature
yyjl0100 2024-12-06 02:09
文献求助 不要just accepted 版本
NaLiRecentProgressandProspectsofSmallMoleculesforNLRP3InflammasomeInhibitionJ.Med.Chem.2023,66,21,14447–14473https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01370#ACS
yyjl0100 2024-09-30 03:46
文献求助 不要just accepted 版本
Xiu-JuanLiuRecentdevelopmentofmulti-targetVEGFR-2inhibitorsforthecancertherapyBioorganicChemistryVolume133,April2023,106425Volume133,April2023,106425...
yyjl0100 2024-09-19 07:13
文献求助 不要just accepted 版本
NathanielW.MabePharmacologicaltargetingofthecancerepigenomeNatureCancer2024volume5,pages844–865(2024)https://www.nature.com/articles/s43018-024-00777-2Nature
yyjl0100 2024-09-19 06:46
文献求助 不要just accepted版本
MarkusSchadeStructuralandPhysicochemicalFeaturesofOralPROTACsJ.Med.Chem.2024,67,15,13106–13116J.Med.Chem.2024,67,15,13106–13116J.Med.Chem.2024,67,15,13106–13116...
yyjl0100 2024-09-13 04:42
文献求助 不要just accepted 版本
GauriMisraTargetedinhibitionofMASTLkinaseactivityinducesapoptosisinbreastcancerLifeSciencesVolume334,1December2023,122250Volume334,1December2023,122250...
yyjl0100 2024-07-31 05:58
11391/46123456下一页