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分类	共搜索到 1279 个相关话题(最多显示前5000个)	作者	最后发表

文献求助	ultimodal brain cell atlas across the adult macaque lifespan XiaoZhang(张潇)1,2,3,49?GuangyaoLai(赖光耀)4,5,49?XiangyuGuo(郭祥玉)6,49Sendemailtoguosapphirejnu.edu.cn?…?YiweiLai(赖毅维)2,3,14,23Sendemailtolaiyiweigenomics.cn?MiguelA...	so_easy	2026-08-24 12:31
生物科学	蛋白质修饰专题：N-糖基化的检测手段及实例解析 5.内核膜N糖仅在内质网合成，不经过高尔基体加工；...质谱检测与数据采集：通过EASY-nLC1200超高效液相色谱系统（UHPLC）对富集后的糖肽进行液相分离，随后耦合QExactiveHF-X高分辨质谱仪，以...	科研战神来了	2026-07-28 01:21
文献求助	Gut microbiota-derived lysine phenylacetylation impairs ... WeiDu1,Jun-YuXu2,YufengLi3,MingyaZhang4,YidanHuang5,ShaoqianZhao6,YingZhou1,LeiZhao7,KexinXu3,LinhuiZhai8,WensiZhao8,JiaLiu3,JiahuiNi3,JunxiaoDai8,TianxianLiu8,JieHong6,...	so_easy	2026-07-10 02:12
文献求助	Single-cell proteome atlas of aging mouse microglia reveals ... HaoranZhang(张浩然)1,11?ZhenLiu(刘震)2,11?BijiaChen(陈碧嘉)3,4,11?GuangxinZhang(张广欣)5,11?LongtengWang(王龙腾)6,11?ChangshengWei(魏昌盛)7,11?XiaohuiZhang(张晓辉)1,10,11...	so_easy	2026-06-12 01:56
文献求助	Farnesylation-driven KRAS phase separation promotes colon ... 2?ZhiyuanXiang1,2?JiangwenMa1,2?LiLi4?HongxueMeng4?XinyuanTong5?HongbinJi6?JianHuang7?YingHu1,2,Farnesylation-drivenKRASphaseseparationpromotescolontumorgrowthcell2026...	so_easy	2026-05-27 11:04
文献求助	β-hydroxybutyrate enhances the metabolic fitness of CAR T ... ShanLiu1,PuneethGuruprasad2,RanjaniRamasubramanian2,BhoomiMadhu3,LucaParuzzo2,KechengHan4,AndreKelly2,AlexanderShestov2,HeNXu5,AlbertoCarturan2,ChaotingZhou6,KevinRAmses7,...	so_easy	2026-03-23 01:14
文献求助	Dual targeting of SLC25A51 and succinate dehydrogenase ... AngJia1,XiaowenZhang2,Ji-HaoZhou3,YongcanMa2,JingWang2,YongboGong2,WenjieSong2,HangchengHu4,YufeiYu2,HaixiaYang2,YouliLu2,LinzhangHuang2,XingrongDu2,ChunmeiChang2,ShanshanPei5,...	so_easy	2026-03-03 01:44
有机资源	2023-Transition‐Metal‐Catalyzed C‐H Functionalization of ... metal-catalyzedC-Hbondactivationreactions?Easy-...155-191)VikashKumar,RajaramMaayuri,LusinaMantry,and,ParthasarathyGandeepanCHAPTER5TransitionMetal-CatalyzedC2andC3...	asymmsyn	2026-02-28 07:31
文献求助	Monitoring Drug Target Engagement in Cells and Tissues Using... TakahiroSeki,EAndreasLarsson,ChenDan,LekshmySreekumar,YihaiCao,P?rNordlundMonitoringdrugtargetengagementincellsandtissuesusingthecellularthermalshiftassayScience.20132013Jul5;...	so_easy	2025-12-25 03:18
文献求助	Tracking cancer drugs in living cells by thermal profiling ... P?rNordlund5,MarcusBantscheff1,GerardDrewesTrackingcancerdrugsinlivingcellsbythermalprofilingoftheproteomeScience20142014Oct3;346(6205):1255784doi:10.1126/science.1255784...	so_easy	2025-12-25 03:25
文献求助	Discovery of broad-spectrum fungicides that block septin-... MinHe#1,JiaSu#1,YoupinXu#1,JinhuaChen#12,MawshengChern#3,MingliangLei1,TuoQi1,ZongkuanWang4,LaurenSRyder5,BozengTang5,MíriamOsés-Ruiz5,KekeZhu1,YuyanCao1,XiaYan5,...	so_easy	2025-12-19 04:52
文献求助	A Streamlined Sequential Enrichment Strategy for Multi-PTM ... GeyiZheng12,LingZhao2,MingxiuLiang2,XiuwenYu2,ChuanxiHuang2,FuchuHe123,...2025doi:10.1021/acs.analchem.5c04541https://pubs.acs.org/doi/10.1021/acs.analchem.5c04541ACS	so_easy	2025-12-12 02:04
文献求助	Identification and application of cell-type-specific ... LingLi1,YimingHuang2,DengyuLu1,JiqiangFu3,LuyanWu4,ZheyuanChen3,HaiouLiao3,JiaqiZhang2,LiLi3,TianyueGu3,FangHe5,HeanLiu3,XiangqingLeng6,JingTang1,JiaqiYan1,CirongLiu3,ChaoLi3,...	so_easy	2025-12-10 01:35
文献求助	Elucidating pathway-selective biased CCKBR agonism for ... Jia-LeWang1,Xue-YingSha2,YueShao3,Zi-HaoZhang4,Shen-MingHuang5,HuiLin6,Shi-YiGan7,NanZhang3,Xin-YiXia8,Yu-NanSun9,Jin-HuiDing10,Rui-QiZhao11,JieCheng12,PanShang13,Jin-PengWang...	so_easy	2025-12-01 02:01
文献求助	Acidosis orchestrates adaptations of energy metabolism in ... SvenGroessl#12,RobertKalis#34,MarteinnTSnaebjornsson5,LeonWambach1,JakobHaider3,FlorianAndersch3,AlmutSchulze5,WilhelmPalm1,...390(6769):eadp7603Science.2025Oct9;...	so_easy	2025-11-28 02:30
文献求助	An archaeal genetic code with all TAG codons as pyrrolysine VeronikaKivenson1,SamanthaLPeters2,GuillaumeBorrel3,AleksandrKivenson,LeahTRoe4,NoahXHamlish5,KhaledFadhlaoui67,AlannaSchepartz4589,SimonettaGribaldo3,RobertLHettich2,...	so_easy	2025-11-28 02:01
文献求助	Epigenetic silencing of interleukin-10 by host-derived ... MarcoDiGioia1?ValentinaPoli1?PiaoJ.Tan2?RobertoSpreafico3?AnneChu1?AlexG.Cuenca4,5?ZhongyangWu6?MehdiBenamar1?LauraPandolfi7?FedericaMeloni7?FatemehAskarian8,9?...	so_easy	2025-11-20 01:17
文献求助	Altered translation elongation contributes to key hallmarks ... DomenicoDiFraia#1,AntonioMarino#1,JaeHoLee#2,ErikaKelmerSacramento1,MarioBaumgart1,SaraBagnoli3,TillBalla4,FelixSchalk1,StephanKamrad5,RuiGuan5,CinziaCaterino1,ChiaraGiannuzzi...	so_easy	2025-11-18 12:49
文献求助	ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and ... ShuaiShao1234,WeiLi1234,YulongHong1234,RuijiangZeng1234,LiangZhu1,LuYi1,YuanLi1,YinhuaiWang1,HaojieHuang5,XuewenJiang678,XinJin1ZDHHC2-...10.1002/advs.202514077...	so_easy	2025-11-11 02:57
文献求助	Cancer cells co-opt an inter-organ neuroimmune circuit to ... YuZhang(张誉)1,2,3,9?YiboGuo(郭毅波)2,3,9?ZheqiLiu(刘喆麒)1,9?YitingSun(孙仪庭)5,9?XiYang(杨溪)4,9?MingtaoChen(陈铭韬)1?GuanyingFeng(冯冠英)1?ChengzhongLin(林承重)1?...	so_easy	2025-11-09 02:49
文献求助	Thermal Proteome Profiling Strategy Identifies CNPY3 as a ... Xiao-WenZhang1,LingLi1,MinLiao1,DanLiu2,AsmaRehman3,YangLiu4,Zheng-PingLiu5,Peng-FeiTu1,Ke-WuZengThermalProteomeProfilingStrategyIdentifiesCNPY3...67(12):10005-100112024Jun27;...	so_easy	2025-11-01 06:49
文献求助	A conserved H3K14ub-driven H3K9me3 for chromatin ... YuanyongHuang,YimeiSun,HongyunQi,...drivenH3K9me3forchromatincompartmentalizationnature15October202515October2025https://www.nature.com/articles/s41586-025-09624-5Nature	so_easy	2025-10-16 01:41
文献求助	Activation of epigenetic reprogramming via crotonylation ... SihongChen12,MengyanZhong3,XiaoyuanWang12,YouweiSu12,YingxiZhao12,SimengWang12,ShougengLiu12,YongshanZhao4,YangZhang4,XinyuFan5,ZongangLiu6,LinaJia1,XuefeiBao3,WeiCui1,...	so_easy	2025-10-16 12:04
文献求助	Unique plasma proteome signatures differentiate adolescent ... XuemeiLi1,YaniGu2,TengTeng1,TingtingLei3,YuqianHe3,SiyuanWang4,XinyuZhou5,CatherineClWongUniqueplasmaproteomesignaturesdifferentiateadolescentmajordepressivedisorder,...	so_easy	2025-10-15 01:14
文献求助	A trimodal protein language model enables advanced protein ... JinSu#1,YanHe#1,ShiyangYou#2,ShiyuJiang1,XibinZhou1,XutingZhang1,YuxuanWang1,XiningSu2,IgorTolstoy3,XingChang4,HongyuanLu5,...10.1038/s41587-025-02836-0...	so_easy	2025-10-14 01:35