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Applications are invited for a Ph.D. position in the newly established Membrane Protein Structural Biology Group at the Department of Biomedical Sciences, University of Copenhagen, Denmark. An important requirement is that the applicant has or is in the process of obtaining a grant from the China Scholarship Council (CSC). The CSC grant will be augmented by the host-laboratory.
The Membrane Protein Structural Biology Group within the Department of Biomedical Sciences works on structural and functional characterizing of membrane proteins that are essential for human health and highly attractive targets in the treatment of disease. The overarching aim is to reveal the molecular principles and determinants of transport processes across cellular membranes for these proteins. To this end, we use a number of complementary techniques centered on X-ray crystallography to study structure-function relationships.
Understanding of the functions and mechanisms of fundamental processes in the cell require structural information, which at the same time leads to applied, biomedical and biotechnological research. The project focuses on structural and functional characterization of membrane proteins which are linked to severe disorders. Research will aim for a detailed understanding of the structure, function, regulation and mechanism of these membrane proteins. A complementary set of methods will be applied centering on biochemical studies probing e.g. mutations. The successful applicant will work in the Membrane Protein Structural Biology Group, but will be expected to visit other sites (such as European synchrotron radiation facilities) occasionally. We are seeking for a highly motivated individual interested in challenging projects. The research will be performed under the supervision of associate professor Pontus Gourdon.
• A master degree in biochemistry (or related discipline) or exam at similar level
• Fluency in English (spoken and written) and good communication skills
Desired qualifications (in two or more listed areas):
• Experience in cloning (primer design, sequencing etc).
• Experience in protein overproduction (particularly Saccharomyces cerevisiae)
• Experience in protein purification (preferably membrane proteins)
• Experience in protein characterization in vitro and/or in cells
• Experience in X-ray crystallography and structural analysis (optimal)
Applicants are encouraged to read more about the research group at http://bmi.ku.dk/english/researc ... structural_biology/ and at http://bmi.ku.dk/english/ regarding the host-department. For more information on working and living in Denmark please see http://ism.ku.dk/ and www.workingconditions.ku.dk. For specific questions about the position, please contact post-doc Kaituo Wang (email@example.com) or associate professor Pontus Gourdon (firstname.lastname@example.org).
Copenhagen is the capital of Denmark and the largest city of the country, situated on the eastern coast of Zealand and immediately connected to Sweden. Through its airport, Kastrup, it is easily accessible from numerous European cities as well as large metropols in America and Asia. The city is the cultural, economic and governmental center of Denmark and offers a rich cultural life and a plethora of events. Copenhagen has nearly 100,000 students enrolled in different universities and institutions. Of these University of Copenhagen is the most dominant and has repeatedly been ranked as one of the best universities in Europe.
The application must include a cover letter (detailing your motivation and background for applying for the specific PhD project), CV, diploma and transcripts of records (including grades), a list of publications (if any), and the names and email addresses of people who can provide a letter of reference. This material should be sent by email, to Pontus Gourdon (email@example.com), Department of Biomedical Sciences, University of Copenhagen.
http://bmi.ku.dk/english/Staff/? ... html&page=1
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