英国诺丁汉特伦特大学招收光纤传感方向博士生一名，奖学金每年18622英镑，雅思要求总分不低于6.5分，小分不低于6分。因为临近截止日期，所以有意报考的同学无须发邮件套磁，直接在线申请就好。背景符合的同学会接到面试通知的。本项目的详细信息与申请链接如下：https://www.ntu.ac.uk/research/f ... itoring-of-implants
The performance of implanted devices, prosthesis and biomaterials are currently only monitored by technologies that offer snapshots of these implants over time in vivo. For example, an earliest CT scan is typically used three months after the surgery to monitor if a spinal fusion cage has fused with vertebral bone to form a strong bonding, hence rendering stability of the implant. However, these implants can fail before or during these snapshots of monitoring. The NHS cost associated with treating patients with failed implants is significant, which adds to the financial pressure faced by NHS. For example, revision in total hip replacement and total knee replacement can cost £70,000 per patient to treat. Therefore, a sensor that can offer continuous and real time measurement of clinically relevant parameters and markers that reflect the level of functionality of an implant and its surrounding environment will offer distinct advantages over current technologies. Markers and parameters provided by the novel sensor will offer information which are previously unavailable to clinicians for improved diagnosis and more accurate prognosis. Providing such real-time monitoring capability will offer opportunity for early intervention and avoid expensive revision surgeries at a later stage.
This project aims to develop an optical fibre-based sensor for measuring mechanical and chemical signals from an implant and its surroundings. The mechanical signals will be the strain and stress experienced by an implant during daily activities. These mechanical parameters are important for orthopaedic devices such as hip replacement or spinal fusion cages where instability or loosening of the implants can cause complications and device failure. Chemical signals including oxygen tension and the concentrations of reactive oxygen/nitrogen species can indicate the status of healing and inflammation which can be linked to implant associated infections, respectively. The project will investigate the seamless combination of the sensor with 3D printed biomaterial scaffolds for tissue regeneration.
This project will be running parallelly with a recently funded 4-year project in which a PDRA will develop optical fibre sensors for measuring maternal contractions to reduce stillbirth. It is envisaged that the student will benefit from working with the PDRA in the laboratory.