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【调剂】北京石油化工学院2024年16个专业接受调剂
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jacob188

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[资源] TAMU招聘博士后:study addiction using 行为学 (or 电生理) and 光遗传学

•        An NIH-funded postdoctoral position is available to investigate synaptic and circuit mechanisms of drug and alcohol addiction. Research in the lab utilizes state-of-the-science technologies, including in vivo dual-channel optogenetic (see our recent paper , https://www.nature.com/articles/s41593-018-0081-9) and chemogenetic (DREADDs, see https://www.biologicalpsychiatryjournal.com/article/S0006-3223(16)32420-9/abstract) manipulation of striatal neuron activities, fiber photometry, rabies-mediated brain-wide neuronal mapping, and FosTRAP approaches in combination with behavioral procedures (e.g., operant alcohol self-administration) and slices electrophysiology. We investigate how medium spiny neurons and cholinergic interneurons in the dorsomedial striatum of the basal ganglia circuitry contribute to alcohol, cocaine, and morphine abuse. For details, please visit https://medicine.tamhsc.edu/faculty/wang.html and http://people.tamu.edu/~jwang188/.
•        We are seeking a highly-motivated behavioral scientist. The successful candidates are expected to have trackable records on operant self-administration, in vivo optogenetic stimulation, or fiber photometry measurement. The ability to stereotaxically infuse viruses in rats or mice is required. Experience with optogenetics, chemogenetics, immunohistochemistry, or confocal imaging is a big plus. The successful applicants are expected to have a recent Ph.D. degree in neuroscience, strong communication skills and writing ability, a record of scientific productivity, and a desire to work independently and cooperatively with a team. The candidate will have opportunities to learn slice electrophysiology.
•        Applicants with solid electrophysiology backgrounds and strong interests in using behavioral approaches are also welcome to apply. The successful candidates are expected to have proven proficiency in slice electrophysiology and will study circuit-specific alterations. Ability to measure glutamatergic plasticity in acute slices using whole-cell patch-clamp recording is desired. Experience with optogenetics, chemogenetics, immunohistochemistry, or confocal imaging is a big plus.
•        The laboratory is equipped with Zeiss microscope/imaging systems, Axon MultiClamp 700B amplifiers/data acquisition systems, Sutter puller and motorized manipulators, Leica Vibratome, Optogenetic light sources, KOPF stereotaxic infusion system, Coulburn operant self-administration chambers, open field chambers, a fiber photometry system, many optogenetic light sources, and PCR machine and workstation. Several common facilities are available within the new building that contains electrophysiological, molecular and behavioral labs.
•        Interested candidates should send Curriculum Vitae and names of three references to Dr. Jun Wang (jwang188@tamu.edu).
•        http://www.tamus.edu/assets/files/benefits/pdf/GuideBooklet.pdf
•        About the institution: Texas A&M University (TAMU) is a research-intensive flagship university of the Texas A&M system. TAMU is the largest university in Texas and the third-largest in the US, with an annual enrollment that exceeds 69,000 students. In 2017, 14,998 graduate students were enrolled among 268 different graduate degree programs. Among the 19 TAMU component colleges, the colleges of liberal arts, sciences, agriculture and life sciences, engineering and veterinary medicine, as well as the Texas A&M Health Science Center (TAMHSC, Medicine, Nursing, Public Health and Pharmacy) are located on a 5,200-acre campus in the twin cities of Bryan and College Station, with a short drive to three major Texas cities -- Houston (1.5 hours), Austin (2 hours) and Dallas (< 3 hours). This vicinity provides not only easy access to big-city life but also less traffic, cheaper housing, county life such as fishing. The George Bush Presidential Library and Museum is one of the region's most popular tourist attractions, with approximately 700,000 visitors annually. Within this campus, there is a large group of neuroscience laboratories, some of which study drug abuse. The department of Neuroscience and Experimental Therapeutics is located in a new building of the Bryan campus, which provides a nice working environment. The postdoc position is a full-time position with benefits. The benefits available to all staff members are outlined here: http://www.tamus.edu/assets/files/benefits/pdf/GuideBooklet.pdf.
•        TAMU招聘博士后:运用行为学(或电生理)和光遗传方法研究药物成瘾机制及治疗
•        国立卫生研究院(NIH)资助的博士后职位,研究药物成瘾的突触和神经环路研究机制。 招聘实验室采用多种研究技术, 包括在体双通道光遗传学(参见我们最近文章https://www.nature.com/articles/s41593-018-0081-9)和化学遗传学(https://www.biologicalpsychiatryjournal.com/article/S0006-3223(16)32420-9/abstract)调控神经元的活动,光纤记录(fiber photometry), Rabies病毒介导的逆行神经元标记,FosTRAP技术, 并结合行为学 (如操作自身给药,operant self-administration)或脑片电生理学。 实验室主要研究基底节神经环路背内侧纹状体内中棘神经元和乙酰胆碱神经元在酒精,可卡因,和吗非成瘾中的作用机制及治疗前景。
•        我们招聘上进心强的, 拥有行为学研究经历的博士后。成功的候选人应在operant self-administration方面拥有可追踪的记录。 需要具有在大鼠或小鼠中立体定向注入病毒的能力。具有光遗传学,化学遗传学,免疫组织化学或共聚焦成像的经验是一大优势。 成功的申请人应获得神经科学博士学位,有较强的沟通能力和写作能力,有可追踪发表的文章, 以及有独立工作能力与团队合作的愿望。 候选人将有机会学习脑片电生理技术。
•        也欢迎具有扎实的电生理学背景并且对使用行为方法有浓厚兴趣的申请人提出申请。 成功的候选人应精脑片电生理学技术,如能够使用全细胞膜片钳记录来测量急性脑片中的谷氨酸能神经传递和可塑性。 具有光遗传学,化学遗传学,免疫组织化学或共聚焦成像的经验是一大优势。
•        有兴趣的候选人应将简历和三个推荐信的名称发送给jwang188@tamu.edu。
•        研究机构简介:德克萨斯A&M大学(TAMU)是德克萨斯A&M系统的研究密集型旗舰大学。TAMU是德克萨斯州最大的大学,也是美国第三大大学,每年的入学人数超过69,000名学生。 在2017年,共有268个研究生学位课程招收了14,998名研究生。在19所TAMU组成的学院中,人文学院,科学学院,农业和生命科学学院,工程学院和兽医学院以及德州A&M健康科学中心(TAMHSC,医学,护理,公共卫生和药学)均位于在布莱恩(Bryan)和大学城(College Station)这两个城市中,校园占地5,200英亩,驱车仅几步即可到达得克萨斯州的三个主要城市-休斯顿(1.5小时),奥斯丁(2小时)和达拉斯(<3小时)。该地区不仅使人们可以轻松地进入大城市,而且交通便利,住房更便宜,还有丰富的休闲生活如钓鱼。乔治·布什总统图书馆和博物馆是该地区最受欢迎的旅游景点之一,每年约有70万游客。在这个校园中,有大量的神经科学实验室,其中一些研究药物滥用。神经科学与实验治疗学系位于Bryan校园的新大楼中,该大楼提供了一个良好的工作环境。博士后职位是具有福利的全职职位。
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