工作地点:
清华大学人环楼
薪金:
面议
学历研究方向:
生物及相关专业本科
招聘岗位:
科研助理
实验室研究方向:激素对于生物的生长发育、新陈代谢和繁衍生息等各种生命活动起重要调节作用;阐明激素的受体识别机制,对于揭示生命现象的本质、提高生物的生存和发展能力具有重要意义。谢道昕实验室主要研究激素感知及其调控植物生长发育和防御反应的分子机制,迄今阐明了茉莉素和独脚金内酯两类激素的受体识别机制:2009年发现的茉莉素受体COI1,遵循生物学领域经典的激素活性分子可逆地结合受体并循环触发信号传导链的“活性分子-受体”识别规律、调控植物的防御反应和生长发育;2016年阐明的独脚金内酯受体D14,则具有生成激素活性分子和不可逆地结合激素活性分子的双重功能、遵循新型的“底物-酶-活性分子-受体”识别规律、调控植物分枝等重要生长发育过程。
实验室近期发表文章:
1. Yan C, Fan M, Yang M, Zhao J, Zhang W, Su Y, Xiao L, Deng H and Xie D. (2018). Injury Activates Ca2+/Calmodulin-Dependent Phosphorylation of JAV1-JAZ8-WRKY51 Complex for Jasmonate Biosynthesis. Molecular Cell, 70(1), 136-149.
2. Yao R, Chen L and Xie D. (2018). Irreversible strigolactone recognition: a non-canonical mechanism for hormone perception. Current Opinion in Plant Biology, 45, 155-161.
3. Yao R, Wang F, Ming Z, Du X, Chen L, Wang Y, Zhang W, Deng H and Xie D. (2017). ShHTL7 is a non-canonical receptor for strigolactones in root parasitic weeds. Cell Research, 27(6), 838.
4. Wu D, Qi T, Li W, Tian H, Gao H, Wang J, Ge J, Yao R, Ren C, Wang X, Liu Y, Kang L, Ding S and Xie D. (2017) Viral effector protein manipulates host jasmonate signaling to attract insect vectors. Cell Research, 27(3), 402.
5. Yao R, Ming Z, Yan L, Li S, Wang F, Ma S, Yu C, Yang M, Chen L, Chen L, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Z, Lou Z and Xie D. (2016) DWARF14 is a non-canonical hormone receptor for strigolactone. Nature, 536(7617), 469. (Featured in Nature and Science Signaling)
6. Qi T, Wang J, Huang H, Liu B, Gao H, Liu Y, Song S and Xie D. (2015) Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell, 27(6), 1634-1649.
7. Qi T, Huang H, Song S and Xie D. (2015) Control of Jasmonate-regulated Stamen Development and Seed Production by a bHLH-MYB Complex in Arabidopsis. Plant Cell, 27(6), 1620-1633.
8. Qi T, Huang H, Wu D, Yan J, Qi Y, Song S and Xie D. (2014). Arabidopsis DELLA and JAZ Proteins Bind the WD-repeat/bHLH/MYB Complex to Modulate Gibberellin and Jasmonate Signaling Synergy. Plant Cell, 26(3), 1118-1133.
9. Song S, Huang H, Gao H, Wang J, Wu D, Liu X, Yang S, Zhai Q, Li C, Qi T and Xie D. (2014) Interaction of MYC2 with EIN3 Modulates Antagonism between Jasmonate and Ethylene Signaling. Plant Cell, 26(1), 263-279.
10. Hu P, Zhou W, Cheng Z, Fan M, Wang L and Xie D. (2013) JAV1 controls Jasmonate-regulated plant defense. Molecular Cell, 50(4), 504-515 (cover story; featured in Mol. Cell)
11. Song S, Qi T, Wasternack C. and Xie D. (2014). Jasmonate signaling and crosstalk with gibberellin and ethylene. Current Opinion in Plant Biology, 21, 112-119.
12. Yan J, Li H, Li S, Yao R, Deng H, Xie Q and Xie D. (2013) The Arabidopsis F-box protein CORONATINE INSENSITIVE 1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway. Plant Cell, 25(2), 486-498. (recommended by Faculty 1000)
13. Song S, Qi T, Fan M, Zhang X, Gao H, Huang H, Wu D, Guo H and Xie D. (2013) The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-mediated Plant Defense and Development. PLoS Genetics, 9(7), e1003653.
14. Qi T, Song S, Ren Q, Wu D, Huang H, Chen Y, Fan M, Peng W, Ren C and Xie D. (2011) The Jasmonate-ZIM-domain Proteins Interact with the WD-repeat/bHLH/MYB Complexes to Control Jasmonate-regulated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis. Plant Cell, 23(5), 1795-1814.
15. Shan X, Yan J and Xie D. (2012) Comparison of phytohormone signaling mechanisms. Current Opinion in Plant Biology, 15(1), 84-91.
16. Song S, Qi T, Huang H, Ren Q, Wu D, Chang C, Peng W, Liu Y, Peng J and Xie D. (2011) The Jasmonate-ZIM-domain Proteins Interact with the R2R3-MYB Transcription Factors MYB21 and MYB24 to Control Jasmonate-regulated Stamen Development in Arabidopsis. Plant Cell, 23(3), 1000-1013.
17. Yan J, Zhang C, Gu M, Bai Z, Zhang W, Qi T, Cheng Z, Peng W, Luo H, Nan F, Wang Z and Xie D. (2009) The Arabidopsis CORONATINE INSENSITIVE 1 protein is a jasmonate receptor. Plant Cell, 21(8), 2220-2236 (recommended by Faculty 1000, featured in Nat. Chem. Bio. and Plant Cell)
工作内容:
1.分子生物学、生物化学、遗传学相关实验技术的全面培训、训练
2.协助老师、学生实验研究
3.完成老师交给的其他工作
工作要求:
1.工作认真严谨、积极主动,为人诚实可靠、具有良好的团队协作精神
2.热爱生命科学,耐得了性子,干得了长久(PS:如果只打算过来混几天就跑的,劝你还是去隔壁拖拖他们的后腿)
工作优势
1.全面得到植物分子生物学、遗传学等理论和实验技能的training,让你从科研小白逐渐具备独立从事科学研究的能力
2.表现优异者,可获得导师推荐信,提供进一步深造学习研究的机会,欢迎有考研读博意向的学生报名
请将个人简历发送至li-r17@mails.tsinghua.edu.cn,我们会对简历进行筛选并及时与你联系,期待优秀的你加入我们的大家庭~
联系人:李睿 18811735100
地址:清华大学人环楼植物信号转导实验室 |