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ZoeyZhao新虫 (小有名气)
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[交流]
【上海】美资公司招聘代谢产物鉴定高级研究员/高级组长
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代谢产物鉴定高级研究员/高级组长 岗位职责： Design and conduct in vitro (enzyme- and cell-based) and in vivo hepatic and extrahepatic biotransformation studies; Propose metabolite structures and CYP and non CYP metabolic pathways in various biological systems. Work proficiently in LC-MS/MS method development, biological sample processing (plasma, bile, urine, feces, plant, tissue), and in detection, identification, structural elucidation and determination of multiple metabolites in various matrices with Q-Trap, Q-Exactive Plus mass spectrometers and NMR, and application of gas phase ion chemistry. Take the responsibility for operation, maintenance & trouble shooting of LC-MS/MS instruments. Maintain accurate records and write study reports for discovery and IND-enabling studies in English and Chinese. Collaborate with bioanalytical and PK scientists to support IND-enabling DMPK study review and designs, and possess good interpersonal communication skills. 任职条件： A M.S.（8-15 year working experience）, or Ph.D(1-7 year working experience). degree in pharmaceutical science, organic chemistry, analytical chemistry, biochemistry, or related discipline with 1- 15 years’ experience in pharmaceutical and biotechnological companies, or contract research organizations. Hands-on experience in designing, conducting, analyzing and reporting in vitro metabolite identification and profiling in liver microsomes and hepatocytes; and designing in vivo drug metabolism studies, and analyzing samples and data, writing reports to support drug discovery and regulatory filing studies. Experience in LC-MS/MS method development, metabolite structure elucidation and determination, mass spectral MS/MS data interpretation, pharmacokinetics and drug metabolism. Working experience with AB Sciex API Q-Trap and/or Thermo Q-Exactive Plus high resolution mass spectrometry instruments. Good interpersonal communication skills and excellent oral and written English and Chinese skill Zoe Zhao Mobile: 15850102685 Mail: zoeyzhao@sipyun.com WeChat :Zoey_ypb [ 来自版块群 上海 ] |
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