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Research Opportunities in Vascular Biology and Disease
The laboratory of Dr. Pengchun Yu in the Cardiovascular Biology Research Program at the Oklahoma Medical Research Foundation (OMRF) is seeking visiting scholars and students to investigate the metabolic regulation of vascular formation and its implications in vascular diseases.
The laboratory, which will formally open in November 2018, will focus on the interface between cellular metabolism and vascular biology. Dr. Yu has recently demonstrated that MYC/hexokinase 2 pathway-driven glucose metabolism in endothelial cells controls blood and lymphatic vessel formation (Yu et al., Nature, 2017). Research projects of the laboratory will be built upon this important finding to further study the crosstalk between metabolic programs and angiogenic signaling events and to understand the involvement of cellular metabolism in the pathogenesis of vascular diseases. Multidisciplinary strategies will be employed, ranging from novel genetically-modified mouse models to cutting-edge systems biology tools including metabolomics and single-cell transcriptome analysis.
OMRF is an independent, nonprofit biomedical research institute. The innovative basic and translational research at OMRF covers several critical areas such as cardiovascular disease, autoimmune disease, and cancer. The Cardiovascular Biology Research Program hosts 10 research groups studying various aspects of cardiovascular biology and provides a highly stimulating and collaborative environment. Moreover, OMRF offers state-of-the-art facilities and outstanding core technology laboratories including imaging, next-generation sequencing, and clinical genomics.
Ideal candidates will need to get funded by the China Scholarship Council or other funding agencies and have extensive experience in molecular and cellular biology or animal surgery. Prior experience in cardiovascular biology is not required. The successful applicants will receive first-rate research training and will be strongly encouraged and supported to publish first-author research papers in the laboratory.
Please send your application along with your curriculum vitae to Dr. Pengchun Yu at Pengchun-Yu@omrf.org.
Contact Information:
Pengchun Yu, Ph.D.
Assistant Member/Professor
Cardiovascular Biology Research Program
Oklahoma Medical Research Foundation
825NE 13th St., Oklahoma City, OK 73104 |
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