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camel9044新虫 (著名写手)
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[交流]
高脂高胆固醇仓鼠模型，用的是male，评审专家问为什么用雄性，如何回答已有5人参与
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In general, both sexes should be included in an animal experiment. Moreover, some clarifications are needed. The abstract needs to be rewritten in quantitative terms--how many hamsters per group, for how long, with what quantitative statistically significant results for key findings? It would be better to note the % fat in the diet rather than calling it "high fat". The introduction should briefly explain why the choice of soybean sterols and why these amounts were chosen. Why were only males used in the study? This practice needs to stop--males and females may or may not respond in the same way to a treatment.Unless there is a specific condition to be studied that require males, both sexes should be studied. 我做的是大豆甾醇调节胆固醇代谢吸收的作用，用的是雄性仓鼠。如何回复呢 |
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