阮志雄,男,博士,广州医科大学南山学者特聘教授,硕士生导师和博士后合作导师,德国哥廷根大学博士,师从著名有机化学家Lutz Ackermann教授。先后在Angew. Chem. Int. Ed.、ACS Catal.、J. Med. Chem.等国际一流杂志发表SCI论文12篇,授权中国专利1篇,其中第一作者8篇(4篇论文影响因子IF>10)。多篇论文被Web of Science评为Highly Cited Paper和Hot Paper。目前,主要从事新药分子的设计、合成与活性研究,以及绿色有机合成与催化方法学研究。
研究方向
1新药分子的设计、合成及其药理学活性评价;
2绿色有机合成与催化方法学。
岗位要求:
博士后:
金属有机化学、有机电合成、药物化学及药学相关专业的博士毕业生,年龄35岁以下。博士期间发表过SCI论文;年薪20到26万。表现优秀者可留校。
项目研究员:
已经或近期将取得硕士或硕士以上学位;有机化学、药物化学及药学相关专业,有电化学背景者优先考虑;发表过SCI论文者优先考虑;良好的英语交流和写作能力;项目研究员年薪12万。
应聘邮箱:zhixiongruan@163.com
近几年发表文章:
1. Zhixiong Ruan, Debasish Ghorai, Giuseppe Zanoni, and Lutz Ackermann,* "Nickel-Catalyzed C‒H Activation of Purine Bases with Alkyl Halides" Chem. Commun. 2017, 53, 9113−9116. (IF = 6.319)
2. Zhixiong Ruan, Shou-Kun Zhang, Cuiju Zhu, Paul Niklas Ruth, Dietmar Stalke, and Lutz Ackermann, "Ruthenium(II)-Catalyzed meta C‒H Mono- and Difluoromethylations by Phosphine/Carboxylate Cooperation " Angew. Chem. Int. Ed. 2017, 56, 2045−2049. (IF = 11.709)
3. Zhixiong Ruan, Nicolas Sauermann, Elisabetta Manoni, and Lutz Ackermann*, "Manganese-Catalyzed C‒H Alkynylation: Expedient Peptide Synthesis and Modification" Angew. Chem. Int. Ed. 2017, 56, 3172−3176. (IF = 11.709)
4. Zhixiong Ruan, Sebastian Lackner, and Lutz Ackermann*, "A General Strategy for Nickel-Catalyzed C–H Alkylation of Anilines" Angew. Chem. Int. Ed. 2016, 55, 3153−3157. (selected as hot paper) (IF = 11.709)
5. Zhixiong Ruan, Sebastian Lackner, and Lutz Ackermann*, "Nickel-Catalyzed C−H Alkynylation of Anilines: Expedient Access to Functionalized Indoles and Purine Nucleobases" ACS Catal. 2016, 6, 4690−4693. (IF = 10.614) |