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西安交通大学代志军教授课题组招收肿瘤学硕士生、博士生（含推免生）
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西安交通大学代志军教授课题组招收肿瘤学硕士生、博士生（含推免生） 代志军教授简历：医学博士，西安交通大学第二附属医院教授，主任医师，研究员，博士生导师。中华预防医学会循证医学分会方法学组副组长，中国医促会循证医学分会委员，中国抗癌协会整合肿瘤专业委员会委员，陕西省肿瘤标志物专业委员会常委，陕西省乳腺癌专业委员会常委，陕西省抗癌协会青委会常委，陕西省肿瘤生物治疗专业委员会常委等多个学会常委或委员，《Cancer Medicine》、《World J Gastroenterol》、《Translational Cancer Research》等SCI杂志编委，国际知名期刊《Oncotarget》、《Medicine》、《Scientific Reports》、《Cancer Chemother Pharmacol》、《Breast Cancer Research and Treatment》、《Journal of Cellular and Molecular Medicine》、《PLOS ONE》、《DNA and Cell Biology》、《BMC Complement Altern Med》、《Tumor Biol》、《Cancer Cell Int》、《Biomarker》、《Journal of Medicinal Food》、《Medical Science Monitor》等10余种SCI杂志审稿人。入选第二附属医院十大科技新星，持续获得院科技新苗、科技骨干人才专项培养计划和西安交通大学优秀青年教师跟踪支持计划资助。近年来在Medicine、JEP、Molecules、Int J Mol Sci、Cancer Cell Int、J Exp Clin Cancer Res、Drug Des Devel Ther等国内外知名期刊发表论文120余篇，其中SCI收录60余篇，中英文被引共计>1100次，最高单篇引用92次。目前主持国家自然科学基金2项、陕西省国际合作重点项目1项及多项省市课题。申请国家发明专利5项。参译《现代外科疾病诊断与治疗》，参编《恶性肿瘤分子靶向治疗》。荣获陕西省青年科技奖、陕西省青年科技标兵、西安新城青年五四奖章、西安交通大学优秀班主任等殊荣。获中国临床肿瘤学科学基金优秀论文一等奖1项，陕西省高校科学技术一、二等奖6项，陕西省政府科技进步奖4项。 近5年发表的主要论文： [1] Liu XH, Lu J, Duan W, Dai ZM, Wang M, Lin S, Yang PT, Tian T, Liu K, Zhu YY, Zheng Y, Sheng QW, Dai ZJ*. Predictive Value of UGT1A1*28 Polymorphism In Irinotecan-based Chemotherapy. J Cancer. 2017 Feb 25;8(4):691-703. (通讯作者，SCI) [2] Wang X, Sun L, Wang X, Kang H, Ma X, Wang M, Lin S, Liu M, Dai C, Dai Z*. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c-Myc expression. Cancer Med. 2017 Mar 1;6(4):788-797. (通讯作者，SCI) [3] Liu D, Wang M, Tian T, Wang XJ, Kang HF, Jin TB, Zhang SQ, Guan HT, Yang PT, Liu K, Liu XH, Xu P, Zheng Y, Dai ZJ*. Genetic polymorphisms (rs10636 and rs28366003) in metallothionein 2A increase breast cancer risk in Chinese Han population. Aging (Albany NY). 2017 Feb 22;9(2):547-555. (通讯作者，SCI) [4] Tian T, Wang M, Zhu W, Dai ZM, Lin S, Yang PT, Liu XH, Liu K, Zhu YY, Zheng Y, Liu M, Dai ZJ*. MiR-146a and miR-196a-2 polymorphisms are associated with hepatitis virus-related hepatocellular cancer risk: a meta-analysis. Aging (Albany NY). 2017 Jan 31;9(2):381-392. [5] Dai Z, Tian T, Wang M, Liu X, Lin S, Yang P, Liu K, Zheng Y, Xu P, Liu M, Yang X, Dai Z*. CTLA-4 polymorphisms associate with breast cancer susceptibility in Asians: a meta-analysis. PeerJ. 2017 Jan 10;5:e2815. (通讯作者，SCI) [6] Zhao Y, Xu P, Kang H, Lin S, Wang M, Yang P, Dai C, Liu X, Liu K, Zheng Y, Dai Z*. Prognostic nutritional index as a prognostic biomarker for survival in digestive system carcinomas. Oncotarget. 2016;7(52):86573-86583.(通讯作者，SCI) [7] Lin S, Wang M, Liu X, Zhu W, Guo Y, Dai Z, Yang P, Tian T, Dai C, Zheng Y, Hu C, Wei L, Dai Z*. Association of genetic polymorphisms in MIF with breast cancer risk in Chinese women. Clin Exp Med. 2016 Nov 14. [Epub ahead of print] (通讯作者，SCI) [8] Lin S, Wang M, Liu X, Lu Y, Gong Z, Guo Y, Yang P, Tian T, Dai C, Zheng Y, Xu P, Li S, Zhu Y, Dai Z*. FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study. Oncotarget. 2016;7(47):78110-78118. (通讯作者, SCI) [9] Ma XB, Wang XJ, Wang M, Dai ZM, Jin TB, Liu XH, Kang HF, Lin S, Xu P, Dai ZJ*. Impact of the PARP1 rs1136410 and rs3219145 polymorphisms on susceptibility and clinicopathologic features of breast cancer in a Chinese population. Transl Cancer Res 2016;5(5):520-528.(通讯作者, SCI) [10] Min W, Liu X, Lu Y, Gong Z, Wang M, Lin S, Kang H, Jin T, Wang X, Ma X, Liu K, Dai C, Zheng Y, Li S, Ma Q, Dai Z*. Association of transcription factor 7-like 2 gene polymorphisms with breast cancer risk in northwest Chinese women. Oncotarget. 2016;7(47):77175-77182. (通讯作者, SCI) [11] Zhai Y, Dai Z, He H, Gao F, Yang L, Dong Y, Lu J. A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility. Oncotarget. 2016;7(45):73935-73944. (SCI) [12] Zhao Y, Dai C, Wang M, Kang H, Lin S, Yang P, Liu X, Liu K, Xu P, Zheng Y, Li S, Dai Z*. Clinicopathological and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) overexpression in colorectal cancer: a meta-analysis. Oncotarget. 2016;7(39):62966-62975. (通讯作者, SCI) [13] Zhao Y, Diao Y, Wang X, Lin S, Wang M, Kang H, Yang P, Dai C, Liu X, Liu K, Li S, Zhu Y, Dai Z*. Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the chinese population. Oncotarget. 2016;7(36):58174-58180. (通讯作者, SCI) [14] Dai ZM, Feng C, Zhang WG, Liu J, Cao XM, Zhang H, Liu Y, Wang M, Liu XH, Dai ZJ*. Lack of association between cytotoxic T-lymphocyte antigen-4 gene polymorphisms and lymphoid malignancy risk: evidence from a meta-analysis. Ann Hematol. 2016;95(10):1685-94. (通讯作者, SCI) [15] Liu K, Liu X, Wang M, Wang X, Kang H, Lin S, Yang P, Dai C, Xu P, Li S, Dai Z*. Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 controls. Oncotarget. 2016;7(39):62954-62965. (通讯作者, SCI) [16] Wang M, Wang Z, Wang XJ, Jin TB, Dai ZM, Kang HF, Guan HT, Ma XB, Liu XH, Dai ZJ*. Distinct role of the Fas rs1800682 and FasL rs763110 polymorphisms in determining the risk of breast cancer among Han Chinese women. Drug Des Devel Ther. 2016;9:4359-4367. (通讯作者, SCI) [17] Wang Z, Liu X, Wang X, Chong T, Lin S, Wang M, Ma X, Liu K, Xu P, Feng Y, Dai Z*. Polymorphisms in TIM-3 and breast cancer susceptibility in chinese women: A case-control study. Oncotarget. 2016;7(28):43703-43712. (通讯作者, SCI) [18] Ren HT, Li YM, Wang XJ, Kang HF, Jin TB, Ma XB, Liu XH, Wang M, Liu K, Xu P, Yao QL, Dai ZJ*. PD-1 rs2227982 Polymorphism Is Associated With the Decreased Risk of Breast Cancer in Northwest Chinese Women: A Hospital-Based Observational Study. Medicine (Baltimore). 2016 May;95(21):e3760. (通讯作者，SCI) [19] Liu X, Wang X, Fu SW, Wang M, Kang H, Guan H, Zhang S, Ma X, Lin S, Liu K, Feng Y, Dai C, Dai Z*. Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study. Oncotarget. 2016;22:32765-32773. (通讯作者, SCI) [20] Guan H, Dai Z, Ma Y, Wang Z, Liu X, Wang X. MicroRNA-101 inhibits cell proliferation and induces apoptosis by targeting EYA1 in breast cancer. Int J Mol Med. 2016;37(6):1643-51. (SCI) [21] Wang M, Wang X, Fu SW, Liu X, Jin T, Kang H, Ma X, Lin S, Guan H, Zhang S, Liu K, Dai C, Zhu Y, Dai Z*. Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population. Oncotarget. 2016;19:27665-27675. (通讯作者, SCI) [22] Dai ZM, Kang HF, Zhang WG, Li HB, Zhang SQ, Ma XB, Lin S, Wang M, Feng YJ, Liu K, Liu XH, Xu P, Dai ZJ*. The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study. Medicine (Baltimore). 2016 Feb;95(7):e2826. (通讯作者，SCI) [23] Dai ZJ*, Liu XH, Kang HF, Wang XJ, Jin TB, Zhang SQ, Feng T, Ma XB, Wang M, Feng YJ, Liu K, Xu P, Guan HT*. Genetic Variation in Metastasis-Associated in Colon Cancer-1 and the Risk of Breast Cancer Among the Chinese Han Population: A STROBE-Compliant Observational Study. Medicine (Baltimore). 2016 Feb;95(6):e2801. (SCI) [24] Dai ZM, Zhang TS, Lin S, Zhang WG, Liu J, Cao XM, Li HB, Wang M, Liu XH, Liu K, Li SL, Dai ZJ*. Role of IL-17A rs2275913 and IL-17F rs763780 polymorphisms in risk of cancer development: an updated meta-analysis. Sci Rep. 2016;6:20439. (通讯作者，SCI) [25] Dai ZJ*, Liu XH, Ma YF, Kang HF, Jin TB, Dai ZM, Guan HT, Wang M, Liu K, Dai C, Yang XW, Wang XJ*. Association Between Single Nucleotide Polymorphisms in DNA Polymerase Kappa Gene and Breast Cancer Risk in Chinese Han Population: A STROBE-Compliant Observational Study. Medicine (Baltimore). 2016;95(2):e2466. (SCI) [26] Liu XH, Dai ZM, Kang HF, Lin S, Ma XB, Wang M, Liu K, Dai C, Wang XJ, Dai ZJ*. Association of IL-23R Polymorphisms (rs6682925, rs10889677, rs1884444) With Cancer Risk: A PRISMA-Compliant Meta-Analysis. Medicine (Baltimore). 2015;94(52):e2361. (通讯作者，SCI) [27] Wang B, Dai ZM, Zhao Y, Wang XJ, Kang HF, Ma XB, Lin S, Wang M, Yang PT, Dai ZJ*. Current evidence on the relationship between two common polymorphisms in NPAS2 gene and cancer risk. Int J Clin Exp Med. 2015;8(5):7176-83. (通讯作者，SCI) [28] Dai ZM, Fei YL, Zhang WG, Liu J, Cao XM, Qu QM, Li YC, Lin S, Wang M, Dai ZJ*. Association of Vitamin D Receptor Cdx-2 Polymorphism With Cancer Risk: A Meta-Analysis. Medicine (Baltimore). 2015;94(33):e1370. (通讯作者，SCI) [29] Zhao Y, Dai Z, Min W, Sui X, Kang H, Zhang Y, Ren H, Wang X. Perioperative versus Preoperative Chemotherapy with Surgery in Patients with Resectable Squamous Cell Carcinoma of Esophagus: A Phase III Randomized Trial. J Thorac Oncol. 2015;10(9):1349-56. (SCI) [30] Liu XH, Li S, Wang M, Dai ZJ*. Current Status and Future Perspectives of Sonodynamic Therapy and Sonosensitiers. Asian Pac J Cancer Prev. 2015;16(11):4489-92. (通讯作者) [31] Dai ZM, Liu J, Cao XM, Zhang Y, Wang M, Liu XH, Li CJ, Dai ZJ*, Zhang WG. Association Between Interleukin-10-3575T>A (rs1800890) Polymorphism and Cancer Risk. Genet Test Mol Biomarkers. 2015;19(6):324-30. (通讯作者，SCI) [32] Liu XX, Wang M, Xu D, Yang JH, Kang HF, Wang XJ, Lin S, Yang PT, Liu XH, Dai ZJ*. Quantitative Assessment of the Association between Genetic Variants in MicroRNAs and Colorectal Cancer Risk. Biomed Res Int. 2015;2015:276410. (通讯作者，SCI) [33] Dai ZJ, Shao YP, Kang HF, Tang W, Xu D, Zhao Y, Liu D, Wang M, Yang PT, Wang XJ. Relationship between apurinic endonuclease 1 Asp148Glu polymorphism and gastrointestinal cancer risk: An updated meta-analysis. World J Gastroenterol. 2015;21(16):5081-9. (SCI) [34] Wang M, Wang XJ, Ma YF, Ma XB, Dai ZM, Lv Y, Lin S, Liu XH, Yang PT, Dai ZJ*. PSCA rs2294008 C > T polymorphism contributes to gastric and bladder cancer risk. Ther Clin Risk Manag. 2015;11:237-45. (通讯作者，SCI) [35] Dai ZJ, Shao YP, Wang XJ, Xu D, Kang HF, Ren HT, Min WL, Lin S, Wang M, Song ZJ. Five Common Functional Polymorphisms in microRNAs (rs2910164, rs2292832, rs11614913, rs3746444, rs895819) and the Susceptibility to Breast Cancer: Evidence from 8361 Cancer Cases and 8504 Controls. Curr Pharm Des. 2015;21(11):1455-63. (SCI) [36] Dai ZJ, Wang BF, Ma YF, Kang HF, Diao Y, Zhao Y, Lin S, Lv Y, Wang M, Wang XJ. Current evidence on the relationship between rs1256049 polymorphism in estrogen receptor-β gene and cancer risk. Int J Clin Exp Med. 2014;7(12):5031-40. (SCI) [37] Ren HT, Wang XJ, Kang HF, Lin S, Wang M, Dai ZJ*. Associations Between C1772T Polymorphism in Hypoxia-Inducible Factor-1α Gene and Breast Cancer: A Meta-Analysis. Med Sci Monit. 2014;20:2578-83.(通讯作者，SCI). [38] Dai ZJ, Wang XJ, Kang AJ, Ma XB, Min WL, Lin S, Zhao Y, Yang PT, Wang M, Kang HF. Association between APE1 Single Nucleotide Polymorphism (rs1760944) and Cancer Risk: a Meta-Analysis Based on 6,419 Cancer Cases and 6,781 Case-free Controls. J Cancer. 2014;5(3):253-9. (SCI). [39] Dai ZJ, Kang HF, Wang XJ, Shao YP, Lin S, Zhao Y, Ren HT, Min WL, Wang M, Liu XX. Association between genetic polymorphisms in AURKA (rs2273535 and rs1047972) and breast cancer risk: a meta-analysis involving 37,221 subjects. Cancer Cell Int. 2014;14(1):91.(SCI). [40] Gao J, Kang HF, Ma XB, Tang W, Liu D, Zhao Y, Zhang SQ, Guan HT, Lin S, Ren HT, Wang XJ, Dai ZJ*. Functional promoter -765 G>C variant in COX-2 gene is associated with the susceptibility of breast cancer in Chinese Han women. Cancer Cell Int. 2014;14:38. (通讯作者，SCI). [41] Dai ZJ, Wang XJ, Zhao Y, Ma XB, Kang HF, Min WL, Lin S, Yang PT, Liu XX. Effects of interleukin-10 polymorphisms (rs1800896, rs1800871 and rs1800872) on breast cancer risk: evidence from an update meta-analysis. Genet Test Mol Biomarkers. 2014;18(6): 439-45. (SCI). [42] Gao J, Kang AJ, Lin S, Dai ZJ*, Zhang SQ, Liu D, Zhao Y, Yang PT, Wang M, Wang XJ. Association between MDM2 rs 2279744309 polymorphism and breast cancer susceptibility: a meta-analysis based on 9,788 cases and 11,195 controls. Therapeutics and Clinical Risk Management. 2014;10:269-77. (通讯作者，SCI). [43] Gao J, Lu WF, Dai ZJ*, Lin S, Zhao Y, Li S, Zhao NN, Wang XJ, Kang HF, Ma XB, Zhang WG. Induction of apoptosis by total flavonoids from Scutellaria barbata D. Don in human hepatocarcinoma MHCC97-H cells via the mitochondrial pathway. Tumor Biol. 2014;35(3):2549-59. (通讯作者，SCI). [44] Dai ZJ, Shao YP, Ma XB, Xu D, Tang W, Kang HF, Lin S, Wang M, Ren HT, Wang XJ. Association of the Three Common SNPs of Cyclooxygenase-2 Gene (rs20417, rs689466, and rs5275) with the Susceptibility of Breast Cancer: An Updated Meta-Analysis Involving 34,590 Subjects. Disease Markers. 2014;2014:484729.(SCI). [45] Dai ZJ, Gao J, Kang HF, Ma YG, Ma XB, Lu WF, Lin S, Ma HB, Wang XJ, Wu WY.Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells. Drug Des Devel Ther. 2013, 7:149–159. (SCI). [46] Dai ZJ, Gao J, Ma XB, Kang HF, Wang BF, Lu WF, Lin S, Wang XJ, Wu WY. Antitumor effects of Rapamycin in Pancreatic Cancer Cells by Inducing Apoptosis and Autophagy. Int J Mol Sci. 2013, 14(1): 273–285. (SCI). [47] Wang BF, Dai ZJ, Wang XJ, Bai MH, Lin S, Ma HB, Wang YL, Song LQ, Ma XL, Zan Y, Min WL, Cheng YA. Saikosaponin-d increases the radiosensitivity of smmc-7721 hepatocellular carcinoma cells by adjusting the g0/g1 and g2/m checkpoints of the cell cycle. BMC Complement Altern Med. 2013;13(1):263. (共同第一，SCI) [48] Dai ZJ, Tang W, Lu WF, Gao J, Kang HF, Ma XB, Min WL, Wang XJ, Wu WY. Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells. Cancer Cell Int. 2013, 13:27. (SCI). [49] Dai ZJ, Lu WF, Gao J, Kang HF, Ma YG, Zhang SQ, Diao Y, Lin S, Wang XJ, Wu WY. Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don. BMC Complement Altern Med. 2013;13(1):150. (SCI). [50] Kang H, Dai Z, Ma X, Ma L, Jin Y, Liu X, Wang X. A genetic variant in the promoter of APE1 gene (-656 T>G) is associated with breast cancer risk and progression in a Chinese population. Gene. 2013;531(1):97-100. (共同第一，SCI). [51] Dai ZJ, Kang HF, Lin S, Bai MH, Ma L, Min WL, Lu WF, Wang XJ. Esophageal cancer with esophageal duplication cyst. Ann Thorac Surg. 2013;96:e15-e16. (SCI). [52] Kang HF, Dai ZJ, Bai HP, Lu WF, Ma XB, Bao X, Lin S, Wang XJ. RUNX3 gene promoter demethylation by 5-Aza-CdR induces apoptosis in breast cancer MCF-7 cell line. OncoTargets and Therapy. 2013, 6:411-417. (共同第一，SCI). [53] Dai ZJ, Li S, Gao J, Xu XN, Lu WF, Lin S, Wang XJ. Sonodynamic therapy (SDT): A novel treatment of cancer based on sonosensitizer liposome as a new drug carrier. Med Hypotheses. 2013, 80(3): 300–302. (SCI). [54] Dai ZJ, Wang BF, Lu WF, Wang ZD, Ma XB, Min WL, Kang HF, Wang XJ, Wu WY. Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in Vitro. Molecules. 2013; 18(1):934–950. (SCI). [55] Dai ZJ, Ma XB, Kang HF, Gao J, Min WL, Guan HT, Diao Y, Lu WF, Wang XJ. Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo. Cancer Cell Int. 2012;12:53. (SCI). [56] Dai ZJ, Gao J, Ma XB, Yan K, Liu XX, Kang HF, Ji ZZ, Guan HT, Wang XJ. UP-regulation of hypoxia inducible factor-1alpha by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells. J Exp Clin Cancer Res. 2012, 31:28(SCI). 基金：项目组目前承担国家自然科学基金4项，陕西省科技统筹项目和陕西省国际合作重点项目各1项，其它省市各级科研课题20余项。共计研究经费200余万元。 1. 2014年国家自然科学基金70万元 2. 2011年国家自然科学基金，23万元 3. 2010年国家自然科学基金，32万元 4. 陕西省科技统筹项目，50万元 5. 西安交通大学青年教师跟踪支持计划，35万元 6. 陕西省国际合作重点项目，10万元 成果获奖： [1] 苦参等中药及其相关制剂抗肿瘤作用机制与应用研究 陕西省高校科学技术奖 一等奖 2017-59 [2] 选择性COX-2抑制剂治疗乳腺癌的系列研究 2016年陕西省科学技术二等奖 [3] 胰腺癌基因靶向治疗及放射增敏相关研究 陕西省高校科学技术奖 一等奖 14O14 陕西省科学技术二等奖 [4] 乳腺癌综合治疗策略的系列研究 陕西省高校科学技术奖 二等奖 09GK-005 陕西省科学技术三等奖 09-054 [5] 乳腺癌中多基因联合检测及其表达的临床意义 陕西省高校科学技术奖 二等奖 05J13 陕西省科学技术三等奖 2005-084 [6] 相关基因以及联合辐射抑制胰腺癌的机制研究 陕西省高校科学技术奖 二等奖 2007006 [7] 2006年中国临床肿瘤学科学基金优秀论文一等奖 研究方向： 1. 乳腺癌分子靶向治疗及免疫治疗基础 2. 肿瘤遗传易感性 3. 清热解毒代表中药抗肿瘤机制 项目组培养的硕士生也均有SCI论文发表。欢迎报考。 E-mail: dzj0911@126.com; dzj0911@xjtu.edu.cn 发自小木虫Android客户端 |
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