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超声自组装纳米粒子,超声波的参数一般为多少啊?

作者 aust知足常乐
来源: 小木虫 150 3 举报帖子
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  • kaka9897

    很想很想问你 你是形成胶束吗?如果是这方面 我可以帮你解答

  • kaka9897

    10 mg copolymer was dissolved  in 1 mL dichloromethane to a form copolymer solution. 10 mL aqueous solution was added to the  copolymer solution and emulsified using sonication for 3 min  (30 W) to get a W1/O emulsion. 2 mL 2% (w/v) PVA aqueous  solution W2 was then added and sonicated for 5 min (80 W) to  make a W1/O/W2 emulsion. The resulting W1/O/W2 emulsion  was then diluted into 10 mL 0.3% (w/v) PVA solution and  the dichloromethane was removed by evaporation under  reduced pressure. The obtained NPs were collected  by centrifugation at 13 000 rpm for 15 min and then washed  three times with distilled water.
    ——Nie X, Zhang J, Xu Q, et al. Targeting peptide iRGD-conjugated amphiphilic chitosan-co-PLA/DPPE drug delivery system for enhanced tumor therapy[J]. Journal of Materials Chemistry B, 2014, 2(21): 3232-3242,

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