SATPdb is a database of structurally annotated therapeutic peptides curated from twenty public domain peptide databases and two datasets. These peptides have wide range of function and therapeutic activities, here we classified these peptides into 10 categories based on their major function. These categories includes anticancer, antiviral, antiparasite, antibacterial, drug delivery and toxic peptides. In addition to main categories, we also assigned sub-categories to peptides belongs to certain peptide categories; for examples toxic peptides were further classified into cytotoxic and hemolytic peptides. It has been shown in past that structure of peptide is responsible to its function. Thus we predicted or annotated structure of peptides in SATPdb using state-of-art techniques and Protein Data Bank (PDB). In order to faciliate scientific community, we integrated numreous web-based tools in this datbase.
abaloparatide 2017年3月刚获批上市。
谢谢楼主整理分享!
顶一下,感谢分享!
SATPdb is a database of structurally annotated therapeutic peptides curated from twenty public domain peptide databases and two datasets. These peptides have wide range of function and therapeutic activities, here we classified these peptides into 10 categories based on their major function. These categories includes anticancer, antiviral, antiparasite, antibacterial, drug delivery and toxic peptides. In addition to main categories, we also assigned sub-categories to peptides belongs to certain peptide categories; for examples toxic peptides were further classified into cytotoxic and hemolytic peptides. It has been shown in past that structure of peptide is responsible to its function. Thus we predicted or annotated structure of peptides in SATPdb using state-of-art techniques and Protein Data Bank (PDB). In order to faciliate scientific community, we integrated numreous web-based tools in this datbase.
入口:http://crdd.osdd.net/raghava/satpdb/
数据库介绍:SATPdb: a database of structurally annotated therapeutic peptides
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702810/,
THPdb:A database of FDA approved therapeutic peptides and proteins
入口:http://crdd.osdd.net/raghava/thpdb/
数据库介绍文献:THPdb: Database of FDA-approved peptide and protein therapeutics
原文链接:http://journals.plos.org/plosone ... ournal.pone.0181748
这个是总的,感兴趣的可以研究一下。
http://crdd.osdd.net/raghava/pepdesi.html
蛋白多肽药物研发新闻
http://www.pipelinereview.com/in ... teins-and-Peptides/