首先按照两个审稿人的意见将文章修改好，写好response, revised/marked-manuscript, letter； 在response中，注意措辞，说明那个反对人的修改意见为什么不对，按1、2、3之类的罗列，这样，审稿人阅读的时候就一目了然，很容易看懂；在给Editor的letter中，指出反对审稿人的错误，同时委婉地要求编辑重新考虑一下。。。

[ Last edited by hqzhou0817 on 2011-2-20 at 14:29 ]

申述也是一个学习的过程。。。。。。。

建议申诉下，呵呵，否则心里不舒服

坚持就是胜利

申诉的困难也很大，但是能学到不少东西，祝福楼主

Dear XX,

Thank you for your and the two Reviewers’ efforts in the review of our manuscript entitled “XXXX” for consideration as XX in XXX. You gave us very important comments and suggestions, which have helped us to improve our manuscript. Reviewer 1 gave us lots of helpful suggestions and thought that our work eventually might be publishable after some revisions. Reviewer 2 thought our manuscript XXXX. We have carefully carried out additional experiments and improved the manuscript as Reviewer 1 and 2 suggested, such as XXXX, which consistently proves our original proposed XXXX. In addition, 更多重要理由 Therefore, we sincerely hope you could reconsider our manuscript for publication in XXXX. The detailed responses to the comments from  the Reviewers are listed as follows:
逐条认真的回复两个审稿人意见，尤其对第二个审稿人意见要有理有据的回复。

[ Last edited by liudb on 2011-2-20 at 15:23 ]，

申述一般都是耽误时间，编辑不理你的话，你也不好改投。楼主先冷静想想吧。